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• Medicare announced negotiated prices for 10 prescription drugs, ranging from 38% to 79% discounts on the drug list prices.
• Price negotiation resulted from a provision of the Inflation Reduction Act, signed into law in 2022.
• While Medicare enrollees should see lower out-of-pocket costs for these 10 drugs starting in 2026, other factors may lessen the impact.

Medicare enrollees are expected to save money on 10 prescription drugs starting in 2026, after the federal government successfully negotiated with pharmaceutical companies to lower list prices for these medications.

The discounts on the list prices range from 38% for the blood cancer drug Imbruvica to 79% for the diabetes drug Januvia.

About nine million Medicare enrollees use at least one of the drugs selected for price negotiation, the U.S. Department of Health and Human Services said August 15 in a news release.

The department estimates that in 2026, enrollees will save a combined $1.5 billion on out-of-pocket costs such as copays at the pharmacy. How much individuals save personally depends on their Medicare Part D coverage.

Taxpayers spent more than $56 billion on the 10 drugs in 2023, HHS said. Had the negotiated prices been in effect last year, Medicare would have saved an estimated $6 billion.

The 10 medications were selected last year for the initial round of price negotiations based on conditions laid out in the Inflation Reduction Act, which was signed into law by Biden in 2022.

Previously, individual Medicare plans were able to negotiate prescription drug prices, but Medicare was banned from using its leverage to negotiate prices for the program as a whole.

All Democrats in Congress voted for the IRA, while all Republicans voted against the bill.

Which drugs are impacted?

Here are the 10 medications selected for this initial round of price negotiations, with the discount off the 2023 list price, according to HHS:

• Januvia (diabetes): 79%
• Fiasp/NovoLog (diabetes): 76%
• Farxiga (diabetes, heart failure, chronic kidney disease): 68%
• Enbrel (rheumatoid arthritis, psoriasis): 67%
• Jardiance (diabetes, heart failure, chronic kidney disease): 66%
• Stelara (psoriasis, Crohn’s disease, ulcerative colitis): 66%
• Xarelto (prevention and treatment of blood clots, coronary or peripheral artery disease): 62%
• Eliquis (prevention and treatment of blood clots): 56%
• Entresto (heart failure): 53%
• Imbruvica (blood cancers): 38%

These drugs represent a range of conditions rather than just one or two.

“What Medicare did with these first 10 drugs is focus on medical conditions that affect the Medicare population more than the general population,” said Robert Slavkin, JD, chair of Akerman LLP’s Healthcare Practice Group.

The negotiated prices will go into effect in January 2026.

Early next year, the U.S. Centers for Medicare & Medicaid Services (CMS) will select up to 15 additional drugs for price negotiation, with lower prices to take effect in 2027. This will be followed by lower prices for up to 20 more Part B or Part D drugs for each year after that.

The pharmaceutical industry has filed several lawsuits to keep the negotiated prices from going into effect. So far, none have succeeded.

The industry has claimed that price negotiation will hamper drug innovation. However, the non-partisan Congressional Budget Office estimates that the IRA will prevent 13 new drugs from coming to market over the next 30 years — out of an estimated 1,300 new drugs.

What could Medicare enrollees save?

Many enrollees will see out-of-pocket savings on the medications that are subject to price negotiations, but it will depend on their Medicare Part D coverage.

HHS gave a hypothetical example of a Medicare enrollee taking Stelara who pays a 25% coinsurance on the drug. Today this would amount to about $3,400 for a 30-day supply. After the negotiated price takes effect, they would pay $1,100 per month.

“If you’re taking one of those 10 negotiated drugs, the odds are, the government will benefit, and you, the patient, will benefit,” said Mark Fendrick, MD, director of the University of Michigan Center for Value-Based Insurance Design.

However, he pointed out that it’s not clear yet what Medicare Part D and Medicare Advantage prescription drug (MAPD) plans will do with these drugs, in terms of formulary placement.

“I believe these first 10 drugs will be placed in really good positions [on the formulary], with lower out-of-pocket costs for patients,” he told Healthline.

“But as the great [baseball player] Yogi Berra said, ‘It’s tough to make predictions, especially about the future,’” Fendrick added.

Slavkin agrees that ultimately the price negotiations will have a positive impact for Medicare and Medicare enrollees.

“The question is, ‘How?’ And I don’t think we know the full answer to that yet,” he said, pointing to the many aspects of the healthcare system that could affect how much enrollees end up paying out of pocket.

This includes pharmaceutical manufacturers, insurers, and pharmacy benefit managers (PBMs), as well as drug rebates, out-of-pocket caps and the Medicare donut hole coverage gap.

In addition, “pharmaceutical companies have programs to help patients pay for their drugs,” Slavkin told Healthline, “which may affect whether price negotiation is going to ultimately have a positive impact on Medicare beneficiaries.”

Unintended consequences of negotiation

The price negotiations could also have unintended consequences that might reduce out-of-pocket savings for Medicare enrollees, said Fendrick. He expanded on these in a recent Health Affairs commentary.

While CMS price negotiation sets a “maximum fair price” for a drug, there are no regulations for how Part D insurers make the drug available. 

For example, insurers could require enrollees to pay a larger percentage of out-of-pocket costs for a negotiated drug. Since patient cost-sharing requirements are often based on a drug’s “list price,” this could help plans recoup their lost revenue.

Plans could also restrict access to drugs with negotiated prices by adding in additional administrative hurdles, such as requiring that physicians obtain prior authorization before prescribing a medication, or asking patients to try other medications first.

“CMS has acknowledged that [these kinds of things] might happen,” said Fendrick, “so it’s really important that we continue to watch to make sure it doesn’t.”

“Because the whole goal of negotiating prices for these drugs is to lower the cost not only for the government but also for the patient,” he said.

Other ways to save on prescriptions

While Medicare price negotiation is one of the most highly publicized healthcare parts of the IRA, Fendrick pointed out three other provisions that will help Medicare enrollees save on their medications even sooner than 2026.

First, the $35 monthly cap on out-of-pocket costs for insulin prescriptions, which went into place last year.

Second, is the removal of cost-sharing for vaccines covered under Part D plans, such as shingles and pneumococcal vaccines. “This is hardly ever talked about, but it’s really impactful,” said Fendrick.

Third, the $2,000 out-of-pocket cap on Medicare enrollees’ prescription drug spending. This takes effect next year.

Connected with the out-of-pocket cap is the Medicare Prescription Payment Plan (MPPP), an optional program that allows people on Medicare to pay for their medicines in predictable monthly installments.

“A lot of older adults on a fixed income can’t pay $2,000, particularly at one time,” said Fendrick, “which can happen if you are taking something like a cancer drug or a drug for an autoimmune condition.”

He suggests people consider signing up for MPPP when Medicare Open Enrollment happens in the fall.

Takeaway

Medicare announced negotiated prices on 10 prescription drugs, with the lower list prices set to take effect in January 2026. The impact on Medicare enrollees will depend on their Part D plan.

The discounted list prices range from 38% for the blood cancer drug Imbruvica to 79% for the diabetes drug Januvia. About 9 million Medicare enrollees use at least one of these drugs.

While price negotiation will likely lower patients’ out-of-pocket costs, insurers could increase cost-sharing for these drugs or restrict access to them through increased administrative hurdles.

• The CDC issued an alert over rising human parvovirus B19 cases, also known as “fifth disease” and “slapped-cheek disease.”
• Most cases are generally mild and occur in children, leading to a fever and trademark bumpy red rash on the face or elsewhere on the body.
• Pregnant people and immunocompromised individuals face the highest risk of parvovirus-related complications.
• Currently, there is no vaccine against this infectious disease.

A highly transmissible virus you may have never heard of is circulating as summer draws to a close.

The Centers for Disease Control and Prevention (CDC) recently received reports of human parvovirus B19 activity among people of all ages in the United States, notably children.

Clusters of parvovirus-related complications among pregnant people and people with sickle cell disease were also identified.

“In the first quarter of 2024, public health authorities in 14 European countries observed unusually high numbers of cases of parvovirus B19,” a CDC health adivsory reported on August 13. “In the United States, there is no routine surveillance for parvovirus B19, and it is not a notifiable condition.” 

The CDC’s alert advises healthcare professionals to screen high risk patients presenting associated symptoms, which include fever and unexplained anemia, and the trademark rash that gave this disease its “slapped cheek” nickname. 

Children who contract parvovirus are more likely to develop a bumpy red rash on their cheeks, whereas adults may develop a rash elsewhere on the body.

Most healthy adults and children are considered low risk for serious illness from this respiratory disease, which is often asymptomatic, and will not require treatment.

“Because Parvovirus B-19 is mostly contagious before symptoms present or in the early stages, the only recommendation is to stay home if [you have a fever],” Jennifer Walsh, assistant professor at George Washington University School of Nursing, told Healthline. “Once the typical childhood rash presents, the individual is no longer considered contagious.”

Other groups, such as immunocompromised adults and pregnant people, face higher risks of parvovirus-related complications. Here’s what you need to know to protect yourself.

How common is parvovirus?

Cases of human parvovirus B19 are increasing among people of all ages, from less than 3% in 2022–2024 to 10% in June 2024. 

According to the CDC, the largest increase occurred in children ages 5–9 years, from 15% in 2022–2024 to 40% in June 2024.

Parvovirus was also detected in plasma donors 19.9% of plasma donors in June, up from 1.5% in 2023. 

While the Food and Drug Administration (FDA) is required to screen donated plasma for parvovirus B19, transmission through plasma transfusions is rare in the U.S., the CDC notes.

Why is it called the ‘slapped cheek’ disease?

Parvovirus (Erythema infectiosum) is transmitted through respiratory droplets and may cause a distinct, red, splotchy rash on the cheeks or other parts of the body.

Also known as “fifth disease,” parvovirus was once listed as fifth among the six common rash-related illnesses in children: measles, rubella, chicken pox, roseola, and Duke’s disease.

According to the CDC, about half of parvovirus infections occur from household exposure, with 20–50% of infections occurring at school or child care settings. 

Parvovirus is considered a seasonal disease, but unlike other seasonal respiratory viruses, such as the flu, it does not occur regularly or yearly. 

Because parvovirus transmission is so common among children, around half of adults have antibodies from prior infection by their 20s, with over 70% having antibodies by the time they reach 40 years of age, the CDC notes.

In many cases, people with parvovirus infection are asymptomatic. Symptoms are generally mild and should resolve within a week. These include:

• rash
• fever
• anemia
• muscle or joint pain
• swelling
• diarrhea
• malaise 

Still, immunocompromised people and adults with certain health conditions may face higher risks of more severe illness.

Pregnant people at high risk for complications

Pregnant people are considered at high risk for serious complications from parvovirus. 

The virus can cross the placenta and infect a developing fetus, which may cause complications such as fetal anemia, abnormal fluid buildup, or fetal loss.

“The major unfortunate aspect of this virus is, if it infects susceptible persons who are pregnant, it can have an adverse effect on them and the fetus that they’re carrying — it can lead to miscarriage,” said William Schaffner, MD, professor of preventive medicine and infectious diseases in the Department of Health Policy at Vanderbilt University Medical Center in Nashville.

“If the fetus survives, the virus can get through the placenta into the baby and cause anemia and liver disease. As you can imagine, that causes a great deal of concern on the part of the parents,” Schaffner told Healthline.

Schaffner said because there is no vaccine against parvovirus, it’s important for healthcare professionals like OB-GYNs to be aware of the current surge in cases.

According to the CDC, most cases of fetal parvovirus infection resolve without adverse outcomes. Still, there’s a 5–10% risk of an adverse fetal outcome. This risk is highest when infection occurs during weeks 9–20 of pregnancy.

For instance, a pregnant woman almost lost her baby at 18 weeks from parvovirus-related anemia, NBC recently reported.

“If people become ill, we can provide them supportive care and reassurance and insights into what is likely to happen,” Schaffner said.

Walsh noted that higher-risk populations “should contact their provider if they believe they have been exposed or suspect they have Parvovirus B-19 to discuss potential testing and management.”

Immunocompromised people are also at risk

In people who are severely immunocompromised, the CDC warns that parvovirus B19 can cause chronic or transient aplastic anemia, which can be life threatening.

Health conditions or statuses that put people most at risk for serious complications from parvovirus include:

• leukemia or other cancers
• chemotherapy
• organ transplant
• HIV 
• chronic hemolytic disorders (i.e., sickle cell disease, thalassemia, hereditary spherocytosis)

Aplastic anemia is usually treated with red blood cell transfusions and intravenous immunoglobulin.

Why isn’t there a vaccine for parvovirus?

Vaccines against other common respiratory illnesses like the flu or COVID-19 do not offer immunity against parvovirus B19.

With parvovirus outbreaks being as unpredictable as they are, why haven’t researchers developed a vaccine?

According to Schaffner, it is likely because parvovirus is not considered a deadly disease. 

He explained that some preliminary research has been done into developing a parvovirus vaccine, but further development may have slowed due to a lack of public awareness about the virus and ongoing vaccine hesitancy. 

“We are in the midst of a great period of vaccine reluctance, hesitancy, and skepticism, and so introducing a vaccine against some weird virus that nobody’s ever heard of probably wouldn’t go over very well,” Schaffner said. 

Increased awareness, further evaluation, and general acceptance of a parvovirus vaccine could lead to additional studies and clinical trials that could reduce the frequency and impact of parvovirus outbreaks, he noted.

Takeaway

The human parvovirus B19, also known as “fifth disease” or “slapped-cheek disease,” is circulating in the U.S.

The CDC received reports of a surge in parvovirus cases, most notably in children, which usually presents as a red rash on the face or other parts of the body.

Most cases of parvovirus are mild, but pregnant people and immunocompromised people face higher risks of serious complications.

This blog post has essential tips and advice if you’re thinking of dipping your feet into the cool water of Britain’s beaches, lakes and rivers. Read our tips on reducing your risk of becoming ill after open water swimming.

• Cottage cheese is gaining traction on social media, with users touting its protein content and abilities to help people feel fuller longer and lose weight.
• Registered dietitians say cottage cheese can be a regular part of a nutritious diet, but some health claims need nuance.
• They also shared some suggestions for healthy ways to dig into cottage cheese.

Some TikTok trends — like luxury handbags, color analysis, and makeup products needed to achieve a bronzed “latte makeup” look — come with a side of sticker shock even with a discount (courtesy of an influencer affiliate).

However, the platform has a favorite snack that’s accessible — as in, under $10 and available at most big-box grocery stores: cottage cheese.

Numerous videos involving this dairy food have hundreds of thousands and even millions of views.

However, TikTok doesn’t exactly have the best track record for providing trustworthy diet and nutrition information.

Yet, some of the claims about cottage cheese trending on the platform start with at least a kernel—or curd—of truth.

Healthline asked dietitians to help separate fact from fiction, and they shared the following seven ways TikTok’s favorite dairy food can boost your health.

Cottage cheese improves gut health

The probiotic content of Greek yogurt has made it a favored food for gut health. However, what about cottage cheese? Experts say it depends on the type you choose.

“Some cottage cheese is cultured — meaning it contains the beneficial bug known as probiotics — not all brands or varieties of cottage cheese are,” says Cara Harbstreet, MS RD LD of Street Smart Nutrition. “Compared to other fermented forms of dairy, such as Greek yogurt or kefir, it’s much less likely to contribute a significant number of CFUs, or colony forming units, that’s typically needed for clinical significance. In everyday terms, you could get some probiotics from cottage cheese, but probably not enough.”

Maddie Pasquariello, MS, RDN, a registered dietitian, agrees and added that some cultures found in cottage cheese that may contribute to a person’s gut health include: 

• Lactococcus Lactis
• Lactobacillus Acidophilus 
• Bifidus cultures

Further digging into the comparison between Greek yogurt and cottage cheese, Pasquariello says that low fat cottage cheeses often contain more calories and protein than their low fat Greek yogurt counterparts. However, the differences are typically negligible.

“Enjoy whichever you prefer best,” Pasquariello says. “If dairy is part of your diet — this isn’t a difference that will make a huge impact on your health either way.”

Pasquariello says the sodium content in cottage cheese is less negligible, but it is often significantly higher than that of Greek yogurt. She recommends being mindful of sodium intake if you consume cottage cheese multiple times daily or weekly.

She also says some people may not tolerate some of the additives, like certain gums, in cottage cheese.

Finally, Pasquariello and Harbstreet added another caveat (that is also true of Greek yogurt): Not everyone tolerates dairy products. For some, consuming cottage cheese can irritate the stomach and digestive system.

“Cottage cheese is not a lactose-free food unless specifically stated on the label, so if you struggle with symptoms of lactose malabsorption, proceed with caution to avoid uncomfortable GI symptoms,” Harbstreet says.

Cottage cheese improves immune health

Cottage cheese may not be high in Vitamin C (a vitamin often touted for its immune system benefits), but some TikTok users claim it has components that could contribute to immune health.

Harbstreet says this claim is “potentially” true.

“It probably comes down to the protein — you’ll notice a pattern here,” Harbstreet says. 

A 2022 review of nutrition’s effect on the immune system pointed to data indicating that protein intake could assist with immune health.

“The immune system relies on many important proteins to function well, and these proteins are synthesized — or built — from individual amino acids that we source from foods in our diet,” Harbstreet says. “Cottage cheese can supply this, as well as other nutrients to support your immune system.” 

Harbstreet says these other nutrients include:

• Vitamin B12
• Vitamin B6
• Small amounts of zinc and choline.

One way to increase the vitamin density of a cottage cheese snack? Add some ingredients.

“When using cottage cheese for a snack with some fruits or vegetables, you provide your body with even more nutrients and antioxidants that promote healthy immune systems,” says Razan Hallak, MS, RDN, LD, of The Ohio State University Wexner Medical Center.

Still, Pasquariello says this claim needs nuance, too.

“If you’re really focusing on immunity, one of the best things you can do is consume more plant-based foods in the form of prebiotics,” she says. ”Prebiotics feed your beneficial gut bacteria and encourage them to thrive so they can, in turn, get rid of the bad stuff.”

Prebiotic sources include:

• Grains
• Vegetables like asparagus and cabbage
• Beans
• Fruits, such as grapefruit, peaches, and bananas

Cottage cheese builds muscle

Hallak explains that protein — which cottage cheese has — plays a critical role in building and maintaining muscle. The 2020-2025 Dietary Guidelines for Americans suggest that most healthy adults consume 10-35% of their daily calories from protein. Others may require more, and cottage cheese can help.

“Athletes and active adults can benefit from eating above the current [recommended daily amount] for protein, which is 0.8 grams per kilogram of body weight,” Harbstreet says. “A half-cup serving of cottage cheese provides 11-plus grams of protein, which can make it easier to hit your intake goals each day. However, don’t bank on it being the answer if you’re not also training and resting.”

However, one caveat Harbstreet says to consider is that protein content varies by the brand, with some reporting 12-14 grams of protein per half-cup serving. So, it’s important to check the nutrition label. 

The American Heart Association also suggests adding moderate to high intensity muscle-strengthening activity, such as resistance or weight training, to your routine each week to improve muscle strength.

Cottage cheese helps with weight loss

It can, but it’s not a miracle food (no food is).

“The thing that ultimately determines weight loss is being in a calorie deficit, so cottage cheese on its own can’t achieve that,” Pasquariello says. “Someone could be eating above their ‘maintenance’ calories and exceed what they’re burning each day, and whether or not cottage cheese is a part of their diet won’t matter.”

However, once again, protein could make this reported benefit accurate for some people.

“Eating a diet that’s higher in protein can help some people improve satiation levels and prevent over-eating, which can then help them better manage their caloric intake and thus their weight,” Pasquariello says. “So, in a sort of roundabout way, consuming more cottage cheese could be beneficial for those hoping to lose weight, as long as they’re not simply tacking it onto their existing diet for the sake of doing so.”

Research from 2020 suggested that high protein diets could assist with weight loss and prevent obesity and obesity-related diseases, but the authors said studies lasting more than 12 months are needed. 

Importantly, Pasquariello says getting protein from other sources is possible if cottage cheese isn’t a food you enjoy. If you do like cottage cheese, the type you choose also matters, as well as what you eat with it.

For example, TikTok’s viral “cottage cheese and mustard diet,” which involves consuming mustard, cottage cheese, raw veggies, and sausage, was previously panned by dietitians for its high sodium content and potential to promote disordered eating.

“Many dairy products, especially those that are full-fat, can hinder someone hoping to lose weight by adding unnecessary calories,” Pasquariello says.

Cottage cheese can help you feel fuller for longer

“The sensation of fullness is subjective, but it stands to reason that the high protein content of cottage cheese could contribute to feeling fuller, longer, compared to meals or snacks that don’t include adequate protein,” Harbstreet says.

Using cottage cheese as a piece — or base — for a balanced meal and snack can further increase feelings of satiety.

“Adding cottage cheese to a breakfast rich in carbs and fiber is a good way to balance out your plate and keep you full longer than if you just had carbs on their own,” Pasquariello says. “If you consider something like a piece of toast and an apple versus a piece of toast, an apple, and a bowl of cottage cheese, you’re likely to stay full for longer with the latter meal.”

Cottage cheese lowers the risk of Type 2 diabetes

Experts say there’s some truth to this claim, but the type of cottage cheese matters.

“Plain cottage cheese helps in managing blood sugar since it is high in protein and low in carbohydrates,” Hallak says. “The high protein content allows blood sugar to stabilize, preventing spikes or drops. However, flavored cottage cheese with added fruits will have extra carbohydrates that may affect blood sugar negatively. Therefore, choosing a plain option and adding your fresh fruits on it would be ideal for your health.”

Also, dairy products have carbohydrates, something people who are at risk for or living with type 2 diabetes are generally advised to consume in moderation.

A 2019 systematic review indicated a link between total dairy product consumption and lower type 2 diabetes odds, particularly for yogurt and low fat dairy consumption. 

However, some TikTok-favored recipes, like cottage cheese cookie dough, may not live up to the health hype.

Harbtreet says influencers often frame the recipes as a higher protein, lower-sugar cookie dough recipe that can satisfy your sweet tooth. 

“Do your due diligence because many of these recipes still feature maple syrup, honey, or other forms of sweeteners — natural or artificial,” Harbstreet says.

One more important note: “Check in with yourself to see if you genuinely enjoy the sensory differences between cottage cheese cookie dough and the real thing,” Harbstreet says. “It’s perfectly fine to skip this and source your dietary protein from more savory foods instead.”

Cottage cheese improves bone health

The National Institute of Arthritis and Musculoskeletal and Skin Diseases notes that calcium can play an important role in bone health, and cottage cheese has it. 

“In general, the consensus seems to be that consuming dairy products, including cottage cheese, could potentially improve bone health and/or prevent fractures in aging populations,” Harbstreet says.

However, it won’t fulfill your daily needs, which depend on age and sex.

“A half-cup serving of cottage cheese provides less than 10% of daily calcium needs, but that can still be an improvement for people concerned about bone health,’ Harbstreet says. 

However,  calcium isn’t the be-all, end-all nutrient for bone health. Harbstreet says cottage cheese also has other essential nutrients for the bones, including:

• Vitamin D
• Potassium
• Phosphorus

If cottage cheese — or dairy in general — isn’t for you, Pasquariello says other calcium-fortified, non-dairy choices include:

• Firm tofu
• Spinach
• Black-eyed peas
• Squash
• Shellfish

Simple ways to enjoy more cottage cheese in your diet

Health experts say there are many simple ways you can enjoy cottage cheese as a healthy snack besides simply eating it plain.

Hallak suggests the following tips to dress up a serving of cottage cheese in a healthy way: 

• With pineapple and chia seeds 
• Egg bites (Mix cottage cheese with eggs and veggies)
• On toast with some veggies (cucumber, tomatoes)
• Added to lasagna with ricotta cheese

And Pasquariello adds that she recommends cottage cheese:

• On sourdough with a drizzle of honey and banana or fresh berries, pumpkin seeds, and cinnamon
• In a dip. For instance, use feta to make a whipped feta and cottage cheese spread. (Bonus: “Add some fresh herbs, lemon zest, and fresh black pepper while blending, and top with pine nuts and a drizzle of olive oil,” Pasquariello says.)
• Swapped for Greek yogurt in the morning (or do half cottage cheese, half Greek yogurt)
• Dolloped in tomato sauce as a swap for full-fat ricotta  

Takeaway

Cottage cheese is easily accessible at grocery stores, and it’s having a moment on social media, where users are touting its high protein content, weight loss benefits, and ability to support gut and immune health.

Dietitians say that cottage cheese can serve up these benefits, but that nuance is required.

The type of cottage cheese and how it’s consumed as part of an overall diet matters. For instance, look for cultured cottage cheese if you’re interested in gut health, and opt for low or no-fat versions without sugar added if you’re working with a doctor to lose weight or reduce your type 2 diabetes risk.

Cottage cheese is versatile and can be added to dips or soups, mixed with fruits and veggies, or enjoyed on its own. 

• A new study found that light to moderate drinking is associated with increased cancer- and disease-related mortality in older adults.
• The findings corroborate mounting evidence showing the harmful effects of alcohol consumption, even for moderate drinkers.
• Public perception around alcohol is shifting, especially for young people, as more people choose to limit their consumption or avoid it altogether to preserve their health.

Everything in moderation — but with caveats. 

As more research confirms the negative health effects of alcohol consumption, even in moderate amounts, long-held beliefs about the purported health benefits of the occasional drink or two are shifting.

A large new study published August 12 in JAMA Network Open found that moderate-level alcohol consumption had no benefit for older adults but raised disease-related mortality risk instead.

The findings are based on health records of more than 135,000 adults ages 60 and older in the United Kingdom with health-related or socioeconomic risk factors.

During initial interviews, participants were asked detailed questions about their alcohol use between 2006 and 2010. Using data from the UK Biobank, researchers found increases in cancer-related and all-cause mortality in low-, moderate-, and high-risk drinkers. 

No associations for moderate drinkers without socioeconomic or health-related risk factors were found. However, low risk drinking was still associated with a higher risk of cancer mortality in this group, while moderate drinking continued to show greater chances of death from cancer and other causes. 

Meanwhile, a new Gallup poll shows young people in the United States increasingly view alcohol as unhealthy.

“There is a pervasive myth that low or moderate alcohol consumption improves health outcomes,” David Cutler, MD, board certified family medicine physician at Providence Saint John’s Health Center in Santa Monica, CA, told Healthline. Cutler was not involved in the study.

“Nothing could be farther from the truth. The fact is that population-wide studies demonstrate that any alcohol consumption can have a negative health impact. So, it is difficult to argue with the general conclusion that alcohol consumption may be dangerous to your health,” Cutler said.

Moderate drinking raises disease-related death risk

This new research highlights what many health experts have long suspected about moderate drinking, despite other studies that may have shown the inverse. 

An older study published in 2000 suggests “significant” reductions in cardiovascular mortality risk from drinking red wine. More recently, a 2020 research review highlighted the health benefits of light and moderate alcohol consumption, including reduced cardiovascular disease and type 2 diabetes. 

Current guidelines for moderate drinking continue to suggest up to 14 grams or 1 drink per day for females and up to 28 grams or 2 drinks per day for males on days when alcohol is consumed. 

In the JAMA study, researchers defined moderate drinking as 20–40 grams of alcohol per day for males and 10–20 grams of alcohol per day for females. This range extends beyond the threshold for current moderate drinking guidelines.

The researchers reported the lowest alcohol-related mortality risks among individuals who consumed no more than 10 grams of alcohol daily (less than 1 standard drink), which became more evident in those with higher socioeconomic status.

“The big picture of the health risks of alcohol should not be ignored,” Cutler said. “Cancer mortality was increased in even the lowest risk drinkers. And if health-related and socioeconomic factors were also present these risks were even greater. So, while some people may find excuses in light alcohol consumption because they lack risk factors for poor outcomes, moderate and heavy drinkers have no such safe haven.”

Daniel Landau, MD, board certified oncologist, medical director of virtual hematology at the Medical University of South Carolina, and contributor for the Mesothelioma Center, told Healthline that alcohol may have been exceptionally harmful to the older adults included in the study because they already had other health issues.

“People who are over the age of 60 often have other comorbidities such as diabetes or heart disease and are already at higher risks of developing cancers,” said Landau, who was not involved in the study. “Adding alcohol on top of these risks seemed to exacerbate these other medical conditions and possibly promote the risk of cancer development.”

Socioeconomic status linked to higher death risk from alcohol

Socioeconomic status was also an important factor researchers used to calculate alcohol-related disease risk. 

Participants in this study were also mostly white, which means the findings do not account for alcohol’s effects on other racial demographics.

Of those who were classified as having light alcohol consumption, preferred wine, and drank only with meals, no negative health outcomes were reported. 

“The theory is that many of these patients were typically of a higher socioeconomic status [and] had more access to care and less comorbidities,” Landau said. “With potentially having a lower rate of diabetes or other medical conditions, the alcohol may not have had the full detrimental effect it did on the rest of the population.”

More young people are avoiding alcohol

A new Gallup poll published on August 13 revealed nearly half (45%) of Americans believe that moderate alcohol consumption may be harmful to health. 

This is a 6 percentage point increase from last year and a 17 percentage point increase from 2018, marking an all-time high for this survey over the past 20 years.

The shifting opinion about alcohol becomes more pronounced among young people.

Around 65% of adults ages 18 to 34 say alcohol negatively affects health. Indeed, there is a growing “sober curious” movement among Gen Zers.

Still, 37% of respondents ages 35 to 54 and 39% of those 55 and older agree that alcohol may cause harm.

Only 8% of people believe that alcohol may have a positive effect, which Gallup notes is the lowest on record.

“The history of alcohol consumption in our society has always been ambivalent about whether this substance is a tonic or a toxin,” Cutler said. “The evidence shows that alcohol, in any amount, can be harmful. Prudent people should give serious thought to whether any alcohol consumption is in the best interest of their overall health.”

Why is alcohol unhealthy?

Exposure to ethanol and formaldehyde is harmful to human health. Alcohol beverages contain these components in varying amounts.

According to the National Institute on Alcohol Abuse and Alcoholism (NIAAA), when alcohol is metabolized by the body, most of the ethanol consumed is broken down by the liver and transformed into a toxic compound called acetaldehyde, a known carcinogen that may lead to DNA damage.

While this acetaldehyde reaction is usually short-lived before it’s broken down into acetate, it may still lead to significant damage, particularly in the liver, where the majority of alcohol metabolism occurs.

Other studies have examined the harmful effects of formaldehyde in many alcoholic beverages, Landau noted.

A 2011 study, for instance, detected toxic formaldehyde in 132 of 508 alcohol beverage samples, which included beer, wine, spirits, and other sources of alcohol.

“The conversion of alcohol to formaldehyde is one of the prevailing theories as to why alcohol is detrimental to our organs, especially our liver,” Landau said. “It is very toxic, and excessive amounts of it are incredibly dangerous.”

Should you stop drinking alcohol?

The shift in public perception about alcohol and mounting evidence showing its potential harm has left many people wondering whether to limit their alcohol intake or avoid it entirely.

In 2023, the World Health Organization (WHO) declared that no amount of alcohol is safe.

The U.S. Dietary Guidelines for Americans, 2020-2025 acknowledges the emerging evidence showing that drinking within the current recommendations may raise the risk of death from all causes, including cancer and heart disease, and advises caution. 

However, a silver lining in the JAMA study suggests that having a drink only with meals could help lower the associated mortality risks.

“I remain a believer in ‘everything in moderation,’” Landau said. “However, people have their own theories on what moderation looks like. I generally advise my patients that having a drink with dinner on a weekend is acceptable, but once we start incorporating daily drinking, that starts to become more excessive.”

Takeaway

Public perception about alcohol is shifting as growing evidence shows the potential harm it may cause to human health. 

A new study found that even moderate alcohol consumption had negative health outcomes for older adults of lower socioeconomic status. 

While that risk was smaller for people of high socioeconomic status or those who only drank during meals, moderate drinking should still be approached with caution.

• The majority of prescriptions in the United States for GLP-1 drug semaglutide were paid with commercial insurance.
• Semaglutide is the active ingredient in anti-diabetes drugs Ozempic and Rybelsus, and the weight loss drug Wegovy.
• Smaller numbers of people paid for GLP-1 prescriptions with Medicaid and Medicare, and even fewer by cash.

A new study shows that commercial health insurance paid for the majority of prescriptions in the United States for the anti-diabetes drugs Ozempic and Rybelsus and the anti-obesity drug Wegovy. This trend was especially true for Wegovovy.

In contrast, much smaller numbers of prescriptions for these drugs were filled using Medicare Part D or Medicaid, with a tiny fraction of people paying with cash.

“Despite the disproportionate burden of obesity in Medicaid and Medicare Part D populations and recent increases in public spending on weight-loss medications, most Wegovy fills were for the commercially insured,” wrote study author Dima M. Qato, PharmD, MPH, PhD, director for the Program on Medicines and Public Health at the USC School of Pharmacy, and her colleagues.

The study was published August 2 in JAMA Health Forum.

Commercial insurance is most commonly used to cover GLP-1 prescriptions

In the study, researchers examined data from IQVIA’s National Prescription Audit PayerTrak. This system covers 92% of prescriptions filled and dispensed at retail pharmacies in the United States.

They looked specifically at prescriptions for semaglutide. This drug is the active ingredient in anti-diabetes medications Ozempic and Rybelsus, and anti-obesity drug Wegovy.

They also examined the type of payment used for the prescriptions — commercial health insurance, Medicaid, Medicare Part D, or cash.

Researchers found that between January 2021 and December 2023, the number of prescriptions filled for semaglutide increased by over 442% (from 471 ,876 to 2, 555 ,308). Of these, over 70% were for Ozempic.

During this period, semaglutide prescriptions increased for all types of payment. However, most of the prescriptions were filled using commercial insurance, particularly for Wegovy.

In 2023, commercial insurance accounted for 61.4% of prescriptions filled for Ozempic, 89.5% of Wegovy prescriptions, and 58.1% of Rybelsus prescriptions.

In contrast, Medicare Part D accounted for only 28.5% of prescriptions filled for Ozempic, 32.9% of Rybelsus prescriptions, and 1.2% of Wegovy prescriptions.

Medicaid accounted for less than 10% of prescriptions filled for all three drug brands in 2023.

A small number of people paid cash for Ozempic and Rybelsus, less than 1% of all prescriptions each.

A larger percentage paid cash for Wegovy — 12.7% of prescriptions in 2021, 2.6% in 2022 and 1.2% in 2023.

This trend may represent increased insurance coverage of this medication over time.

What the new study reveals about GLP-1 medication coverage trends

Robert Klitzman, MD, professor of psychiatry and director of the Master of Science in Bioethics program at Columbia University, said that the results of the new study are important, but they don’t give us the whole picture. Specifically, why these prescription trends are happening. 

For example, are people with Medicare and Medicaid less comfortable asking their doctor to prescribe one of these drugs for weight loss? And how many people stop taking the drug after a few months, and does it vary by the type of insurance?

“There’s room for more research here to find out why there are differences in the number of people on Medicare, Medicaid, and private insurance taking these medications,” said Klitzman.

However, he pointed out that in 2022, 54.5% of Americans had commercial insurance, 18.8% had Medicaid and 18.7% had Medicare, according to the US Census.

“So the distribution of prescriptions found in the JAMA Health Forum article is not as alarming as one might initially think,” Klitzman, author of Doctor, Will You Pray for Me?: Medicine, Chaplains, and Healing the Whole Person, told Healthline.

Also, he said the fact that patients on Medicare are more likely than others to be on Ozempic or Rybelsus is not surprising “since these people are older and hence more likely to have heart disease or stroke, which would make them eligible for these medications.”

A glimpse into how the U.S. is tackling the obesity epidemic

Overall, Klitzman thinks this study only provides a glimpse into how well the United States is handling the obesity epidemic.

More than two in five American adults are living with obesity, according to the Centers for Disease Control and Prevention. Rates are higher among Black adults and adults with lower levels of education.

Newer GLP-1 drugs have been shown to be very effective at helping people lose weight and keep the weight off — as long as they keep taking the medication — but Klitzman thinks this is only part of the solution.

“You certainly want to have a good treatment [such as GLP-1s] available to everyone,” he said, “but I wouldn’t want people to think, ‘all we need is for everyone to take a medication and we’ll all be treated.’”

Eating healthy, staying physically active and learning to  deal with stress can also help people lose weight, while offering other benefits.

“Exercise helps you not just lose weight, but it helps with your cognitive thinking and it helps with your heart,” said Klitzman.

However, Lydia C. Alexander, MD, president of the Obesity Medicine Association and chief medical officer of Enara Health, cautions against thinking that people should skip the GLP-1 drugs and only try to lose weight with diet and exercise, something that fuels the stigma surrounding obesity.

People with obesity sometimes get judged for “not taking good care of themselves” or “not trying as hard as they can to maintain a healthy weight,” she told Healthline.

“This thinking is very common, even among primary care physicians,” she added.

While nutrition, physical activity and lifestyle changes are essential to treating obesity, “obesity is a disease,” Alexander said, “and just like any other disease, a medication may also be needed.”

“Because obesity is a metabolic dysfunction, where the body is no longer getting the correct signals to maintain a healthy weight,” she said.

GLP-1 coverage varies across healthcare plans

One limitation of the new study is researchers did not have information on why people were prescribed semaglutide, which may have affected prescription rates.

Ozempic was initially approved for the treatment of type 2 diabetes, and later to reduce the risk of serious heart problems in adults with cardiovascular disease who living with overweight or obesity.

This drug is also sometimes prescribed off-label to help people lose weight, something that was especially common before Wegovy was approved in June 2021 by the Food and Drug Administration as an anti-obesity drug.

The extent of coverage for semaglutide and other GLP-1 medications depends upon the type of health insurance — and the condition it is prescribed to treat.

“Medicare Part D will cover GLP-1 medications when they are used to treat type 2 diabetes or people with pre-existing cardiovascular disease who need to lose weight,” said Alexander.

But “there’s an actual clause that prohibits treating obesity [alone] as part of Medicare,” she said. As a result, the Medicare population does not have GLP-1s readily available to them for all uses.

With Medicaid, GLP-1 coverage varies from state to state since these are state-run programs.

“For example, in Arizona, it’s relatively more difficult to have Medicaid cover anti-obesity medications,” said Alexander, “but in California, these drugs are included as part of Medicaid coverage, and many times without prior authorization needed.”

Among commercial insurance plans, coverage also varies. 

However, a recent survey found that one-third of employer health plans said they are covering GLP-1 drugs for both diabetes and weight loss. This is an increase from around one-quarter in 2023.

In addition, over half of employer health plans cover GLP-1 drugs only as a treatment for type 2 diabetes, the report from the International Foundation of Employee Benefit Plans found.

However, of employers with GLP-1 coverage only for diabetes, almost one-fifth said they are considering offering the drugs for weight loss.

How to find out if your insurance covers GLP-1 drugs like Ozempic

To find out if your health insurance plan covers GLP-1s for weight loss, check the plan’s formulary and summary of benefits and coverage (SBC). This information should be available on your insurance company’s website.

Ro, a direct-to-patient healthcare company, also recently launched the GLP-1 Insurance Coverage Checker, a free tool to help people find out if their insurance covers treatment with GLP-1 medications.

The company said in a news release that nearly half of its patients have coverage for GLP-1s for weight loss, and most have coverage for more than one medication.

In addition, about two-thirds of patients with coverage paid less than $100 per month, the company said. However, most companies require people to get prior authorization before accessing the drugs.

The list price for Wegovy is almost $1,350 for a month’s supply. This is the amount people without insurance coverage would pay before any discounts or rebates. Drugmaker Novo Nordisk also offers a savings card that allows people to pay cash for a one-month supply for $650.

Takeaway

Researchers found that between 2021 and 2023, the majority of prescriptions in the United States for anti-diabetes drugs Ozempic and Rybelsus, as well as the anti-obesity drug Wegovy, were paid with commercial health insurance. The trend was especially strong for Wegovy.

Smaller numbers of people paid for prescriptions with Medicare or Medicaid, which may reflect fewer Americans having these health plans. However, Medicare does not offer coverage for Wegovy, and Medicaid coverage of GLP-1 drugs varies across states.

The study provides a glimpse into how well the country is tackling the obesity epidemic, but experts say more information is needed. For example, why are there differences in prescription rates across insurance, and how many people are prescribed these drugs solely for weight loss?

• Cannabis use is associated with greater risk of developing head and neck cancer, according to a new study.
• Participants had to meet criteria for cannabis use disorder, but the study didn’t include specific information on cannabis consumption.
• Prior research on the association between cannabis consumption and head and neck cancer has been inconsistent.

Cannabis use is strongly associated with the development of head and neck cancer, concludes a sweeping retrospective study of two decades of medical records.

Tobacco and alcohol are already two well-known risk factors for developing head and neck cancers, which include oral and throat cancer. Yet prior research on the risks of cannabis on these cancer types has been inconsistent.

Like tobacco, smoking is a popular way to consume cannabis. Smoking cannabis is known to result in some of the same chemical components as tobacco smoke, which can cause inflammation in the mouth, throat, and lungs — a known cancer risk factor.

A new study published August 8 in the journal JAMA Otolaryngology-Head & Neck Surgery found that cannabis users who met the criteria for cannabis use disorder (CUD) were between 3.5 and 5 times more likely to develop any form of head and neck cancer than those without CUD.

“Our study is the first and the largest to show that there is this association,” said Niels Kokot, MD, a head and neck surgeon with Keck Medicine of USC, and senior author of the study.

“I would consider this a starting point to truly define what the risk is of developing head and neck cancer from cannabis use. It creates an association, but we definitely have more work to do in terms of truly defining what those risk levels are,” Kokot told Healthline.

Head and neck cancer risk 5 times higher among cannabis users

Kokot and his team utilized health records for millions of patients across 64 healthcare organizations in the United States over 20 years.

Among the patients included in the study, 116,076 had a diagnosis of CUD, while nearly 4 million did not. 

Patients had no prior history of head and neck cancer. However, there were some demographic differences between those with CUD and those without.

The CUD group skewed younger, with an average age of 46 years old, compared with an average age of 60 in the other group. There were also slightly less women among those diagnosed with CUD (44.5% versus 54.5%).

Researchers then investigated the risk of developing any form of head and neck cancer and site-specific cancers in the two groups.

To strengthen any association, the study used multiple timeframes: 1 year and 5 years between cancer development and CUD diagnosis, and any amount of time between the two events. 

Depending on the timeframe, patients with CUD were 3.5 to 5 times more likely to develop any form of head and neck cancer.

Laryngeal cancer, a form of throat cancer, had the strongest individual association with CUD and carried more than an 8-fold increased risk.

Oropharyngeal cancer, a throat cancer that affects the pharynx, showed a nearly 5-fold increase. These findings are similar to prior studies that examined the risk of smoking tobacco and head and neck cancer risk.

Other cancers, including oral, salivary gland, and nasopharyngeal, were associated with a 2–3 times increased risk.

Cannabis consumption, dosage not understood

Despite the strength of the findings, the study does contain some significant limitations, which Kokot acknowledged.

Hospital health records do not contain specific information about a patient’s cannabis use frequency, dose, or route of administration, only that they were diagnosed with CUD. 

The authors also note that CUD is likely associated with tobacco and alcohol use, a potential confounding factor. Although they attempted to control for these variables, they note “differences in dosage…may remain” between those diagnosed with CUD and those who were not.

John B. Sunwoo, MD, director of Head and Neck Cancer Research at Stanford Medicine, told Healthline the study was robust but agreed it had limitations. Sunwoo wasn’t affiliated with the research.

“They tried to control for other factors by taking the two different cohorts and balancing out all of the different potential variables like smoking and alcohol. But alcohol use and smoking use was higher proportionally in the cannabis use group,” Sunwoo said.

Since the study relied only on medical records that indicated a patient had CUD, additional details about cannabis use, including frequency, potency, and route of consumption are not present. As a result, the different types of cannabis consumption, such as smoking versus eating were not able to be differentiated.

“In terms of actually looking at the type of usage, such as edibles versus inhaled, or the amount per day or the amount per week and the number of years, we didn’t have that information within the database that we looked at,” Kokot said.

Questions surrounding whether smoking cannabis is more harmful than ingesting it remain unanswered. There is also no clear threshold for the frequency of cannabis use and an association with increased risk of head and neck cancer.

“We can’t draw any conclusions about those factors,” Kokot said. “That’s where additional information would be needed in the next step of research to try to really parse out the risk level in different types of consumption and quantity of consumption.”

Prior research on cannabis, head and neck cancer inconsistent

Tobacco is recognized as the greatest risk factor for developing head and neck cancer. Alcohol consumption is associated with up to a 5-fold increase in risk for various forms of head and neck cancer.

Individuals who consume both alcohol and tobacco together have a substantially higher risk of developing head and neck cancer.

Meanwhile, studies investigating the association between cannabis and head and neck cancer have been inconsistent, explained Paul Armentano, deputy director of the National Organization for the Reform of Marijuana Laws (NORML). This lack of robust evidence is also acknowledged by the study authors.

For instance, a 2015 study found no association between cannabis usage and the development of head and neck cancer. Another study from 2009, found an inverse relationship between the two, indicating that “moderate” cannabis consumption was associated with reduced risk of developing head and neck cancer.

“Given these historically inconsistent results and the potential issue of confounding, further research is necessary before drawing any sort of definitive conclusions,” Armentano told Healthline.

“In the interim, those who consume cannabis regularly — such as medical cannabis patients — may wish to consider alternative delivery methods that either reduce or eliminate the intake of combustive smoke,” he noted.

Sunwoo shared a similar opinion. “There are limitations for the study, and I think people should be aware of those limitations,” he said. “But I also think it should encourage people to investigate this further because we just don’t know.

Understanding cannabis use disorder

CUD is recognized as a psychiatric disorder, however, the criteria for meeting the diagnosis can be murky, leaving the diagnosis largely at the discretion of a doctor.

To meet the criteria, a patient must meet 2 out of 11 criteria. These include:

• taking large amounts of cannabis
• cravings for cannabis
• withdrawal symptoms when not using cannabis
• persistent desire to cut down with unsuccessful attempts
• continued usage despite social or interpersonal problems
• tolerance

Frequency or quantity of use are not objectively defined as part of CUD diagnosis.

Takeaway

New research found that cannabis use disorder (CUD) was associated with a 3.5 to 5 fold increase in risk of developing head and neck cancer. 

Certain site-specific forms of cancer, such as throat (laryngeal), showed up to an 8-fold increase in risk associated with CUD.

Prior studies on the association between cannabis use and these cancer types have been inconsistent. More studies are needed to determine whether ingesting cannabis could have the same impact on head and neck cancer risk as smoking it.

• Actor Daisy Ridley spoke in an interview about her Graves’ disease diagnosis.
• Graves’ disease is an autoimmune condition that causes excess thyroid hormone.
• Symptoms can include rapid heartbeat, weight loss, and protruding eyes.
• It might be caused by a genetic predisposition combined with environmental triggers.
• Treatment can involve medications, surgery, and lifestyle changes.

“Star Wars” star Daisy Ridley revealed in the August 6, 2024, issue of Women’s Health that she was diagnosed with Graves’ disease in September of 2023.

According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Graves’ disease is an autoimmune disorder affecting the thyroid, a small gland in the front of the neck often described as being shaped like a butterfly.

Graves’ disease occurs when the immune system begins to attack the thyroid as if it is an outside invader, causing the gland to become overactive. NIDDK explains that this can cause the body’s functions to speed up.

Ridley told the magazine that she first realized that something was not right when she began to experience hot flashes and fatigue after the completion of her movie Magpie, in which she plays a woman involved in a troubled relationship.

“I thought, Well, I’ve just played a really stressful role; presumably that’s why I feel poorly,” she told Women’s Health.

Upon learning of her symptoms — which also included hand tremors, a racing heart, and weight loss — her primary care doctor referred her to an endocrinologist, who diagnosed her as having the autoimmune condition.

Ridley additionally described to the publication how it felt to finally understand why she had felt so bad: “It was funny, I was like, ‘Oh, I just thought I was annoyed at the world,’ but turns out everything is functioning so quickly, you can’t chill out.”

Ridley has also previously spoken about her diagnoses of endometriosis and polycystic ovarian syndrome (PCOS), which research suggests are linked with a higher risk for Graves’ disease.

What are the symptoms of Graves’ disease?

Micheal O. McKinney, MD, a physician with Healthy Outlook, said that Graves’ disease results in the excessive production of thyroid hormone, a condition known as “hyperthyroidism.”

When this occurs, it can have various metabolic and systemic complications, he explained.

Some of the symptoms you might experience, per McKinney, include:

• Unusual or very fast heartbeats
• Weight loss, even if you eat more than you need
• Anxiety and being easily annoyed
• Trembling hands or fingers
• Inability to tolerate heat accompanied by perspiration for no reason
• Protruding eyes (Graves’ ophthalmopathy)
• Fatigue and muscle weakness
• Enlarged thyroid gland, also known as “goiter”

“It’s worth mentioning that these symptoms develop gradually over time, so they may resemble other illnesses,” he added, “thus demanding specific testing for accurate diagnosis.”

How to reduce your risk of Graves’ disease

John Lowe, MD, a physician at Restore Care, explained that the exact causes of Graves’ disease are unknown.

However, certain factors such as genetic predisposition and environmental triggers may contribute to its occurrence, he said.

To minimize your risk, Lowe said, “Relax through practicing yoga, meditation, and physical exercises effectively.”

“Avoid smoking since it increases the risk and severity of Graves’ ophthalmopathy,” he added. Graves’ ophthalmology is a condition in which swelling around the eyes makes them bulge out.

Additionally, you’ll want to be consistent about getting medical checkups of your thyroid health, especially if you have a family history of thyroid conditions, said Lowe.

Treatments for Graves’ disease

Lowe described several medical treatments for Graves’ disease. Among these are:

• Antithyroid Medications. “These drugs reduce the production of thyroid hormones and may then bring their levels back to normal,” he said.
• Radioactive Iodine Therapy. This treatment involves taking radioactive iodine by mouth in order to destroy the overactive cells, per Lowe.
• Beta-Blockers. “Such medications are useful in managing symptoms like fast heartbeats and tremors,” he said, “but they do not address the underlying cause of hyperthyroidism which is associated with them.”
• Surgery. Lowe said that sometimes, if other treatments haven’t worked or are not appropriate for the patient, it may be necessary to perform a thyroidectomy to remove all or part of the gland.
• Lifestyle Adjustments: “Eating healthy foods, regular exercise, and stress management techniques can help to promote overall well-being as well as alleviate some of the symptoms,” he said.

Lowe concluded by noting that Graves’ disease is treatable through both medical intervention and lifestyle changes.

“It is important to diagnose and treat it early enough since any delay may lead to complications as well as affect one’s quality of life significantly,” he said.

Takeaway

“Star Wars” actress Daisy Ridley revealed in a Women’s Health interview that she had been diagnosed with Graves’ disease, an autoimmune thyroid condition that causes an overproduction of thyroid hormone.

It can lead to symptoms of thyroid hormone excess, such as weight loss, rapid heartbeat, and protruding eyes.

The causes of Graves’ disease are unknown, although it may be due to a combination of genetic predisposition and environmental triggers.

However, it can be treated with medications, surgery, and lifestyle adjustments.

• A new study compared the keto diet with a diet low in added sugars and found that both diets reduced fat mass compared to a control diet.
• However, the keto diet was associated with negative metabolic changes, such as raised “bad” cholesterol and changes in the gut microbiome.
• The diet low in added sugars was not linked to negative health outcomes.

A diet low in added sugars is recommended for overall health. The World Health Organization (WHO) recommends that free sugars make up less than 10% of total energy intake because of their links to chronic diseases.

Studies have shown that reducing intake of free sugars helps reduce fat mass. Similarly, carbohydrate restriction, as with the ketogenic diet, is a proven weight loss method that has recently exploded in popularity.

A new study published in the journal Cell Reports Medicine investigates how the low carb, high fat keto diet compared to a diet low in free sugars (sugar added to foods or drinks) and a control diet. The researchers wanted to find out how these eating patterns influenced weight loss and metabolism. The study involved 53 participants and ran for 12 weeks.

According to a news release, the scientists also found that compared with the control diet, the low-free sugar diet and keto diet reduced fat mass by 2.1 and 2.9 kilograms, respectively. They determined this weight loss was unrelated to changes in physical activity — all groups maintained similar activity levels.

However, the scientists found the keto diet increased levels of “bad” cholesterol and other markers associated with cardiovascular disease risk compared to the low-free sugar diet and the control diet. The keto diet was also linked to reduced “good” gut bacteria.

Meanwhile, the diet low in free sugars did not have these negative side effects.

Can a keto diet cause high cholesterol?

Participants following the keto diet had elevated levels of low-density lipoprotein (LDL) cholesterol, sometimes called “bad” cholesterol. 

In particular, they had higher levels of small and medium-sized LDL particles. When it comes to cholesterol, the smaller the particle, the worse it is for health.

In contrast, the low-sugar diet significantly reduced LDL cholesterol.

Participants following the keto diet also had increased levels of a molecule called apolipoprotein B (apoB), a compound found in LDL cholesterol. This protein is linked to atherosclerosis, where the lining of blood vessels develops plaques, increasing the risk of cardiovascular disease.

“This is a meaningful reduction,” study author Javier Gonzalez, PhD, a professor at the University of Bath in the United Kingdom, told Healthline.

“We observed a 0.5 millimoles per liter (mmol/L) reduction. Genetic studies indicate that if the levels of LDL cholesterol were reduced by just 0.35 mmol/L, then over a lifetime, this would equate to a 21% lower relative risk of atherosclerotic cardiovascular disease, including heart disease and stokes,” Gonzales said.

How does the keto diet affect gut health?

Unlike the reduced-sugar and control diets, the keto diet significantly affected the gut microbiome — the trillions of bacteria that live in the lower intestine.

In particular, they found reduced Bifidobacteria, a “good” gut bacteria. Reduced numbers of these species are linked to increased risks of metabolic, immune, and gut issues.

Bifidobacteria also produce important B vitamins and other compounds that support overall health.

Fiber — a carbohydrate that the digestive system cannot break down — feeds our gut bacteria. Fiber intake is severely reduced on the keto diet, which may explain why this dietary pattern would impact the microbiome.

Keto diet impairs glucose tolerance

Carbohydrates are broken down into glucose in the gut. Glucose then enters the bloodstream and travels around the body. This is healthy, but if levels stay too high for too long, blood vessels may become damaged.

In response to rising blood glucose levels, the body releases insulin, which helps the liver and muscles take up the glucose and reduces the levels in the blood.

In this study, those following the keto diet had lower glucose levels in their blood before eating.

However, participants also had reduced glucose tolerance. In other words, glucose was removed from their blood less efficiently after eating, which would cause a longer blood sugar response.

What are the long-term effects of the keto diet?

When asked what these keto-related metabolic changes might mean in the long run, Gonzales explained this is a “challenging question to answer.”

Some metabolic changes determined by this study were beneficial (i.e., lower fasting glucose levels), and some were negative (i.e., the increase in apoB).

“This may mean that the long-term effects on health depend on the status of the individual,” Gonzales said. “For example, does someone have a particular problem with controlling their fasting glucose or their blood lipids?” 

Gonzalez said he plans to continue this research. “We are keen to explore if there are individual responses to ketogenic diets that may warrant personalized use and whether we can mitigate against some of the unfavorable effects with targeted supplementation strategies,” he said.

“We have just received a large Medical Research Council grant for some of this work and are actively seeking more funding for the rest.”

Sarah Herrington, a nutritionist for Brio-Medical, explained the potential long-term implications of following the keto diet: “Long-term effects of a ketogenic diet may include more significant changes to the gut microbiome, potentially leading to less overall diversity.” 

“It may also worsen glucose tolerance — the body will be more sensitive to sugars and carbohydrates when they are reintroduced into the diet,” Herrington continued.

“A ketogenic diet is more likely to alter the way the body uses energy, increasing fat metabolism and making positive short-term improvements in blood sugar regulation, but may have implications in the health of the microbiome long- term.”

Takeaway

Restricting free sugars or following the keto diet can lead to weight loss. But a new study shows the keto diet may have negative health consequences, such as raising bad cholesterol and harming gut health.

However, a diet low in added sugars did not appear to harm health.

“The free sugar restriction achieves this with almost entirely favorable health effects, whereas the ketogenic diet achieves the weight loss with some trade-offs we may need to be cautious about,” Gonzales said.

• TikTokers are drinking Ricezempic – a drink made from discarded rice water – to aid weight loss. 
• They claim that the drink is full of resistant starches that suppress appetite and help you feel full for longer, similar to GLP-1 drugs like Ozempic and Wegovy.
• Experts say resistant starches may aid feelings of fullness but that Ricezempic isn’t a viable weight loss aid.

Another weight loss hack has gone viral on TikTok. This time, it’s Ricezempic, a homemade drink that users claim mimics the effects of GLP-1 weight loss drugs like Ozempic, Wegovy, and Zepbound.

The drink is made by soaking uncooked rice in water for a short period of time, removing and discarding the rice, and then drinking the water.

TikTokers say it’s best consumed first thing in the morning before you eat. 

The claim? Proponents say the drink triggers weight loss because it contains resistant starches. They claim that this suppresses your appetite and allows you to feel fuller for longer, similar to Ozempic. 

One TikToker even claims that they have lost 27kg (59 lbs) in two months by drinking Ricezempic. 

So, can this drink really mimic the effects of GLP-1 drugs and trigger significant weight loss? Health experts aren’t convinced. 

Ricezempic and weight loss: is there a link?

Lisa Moskovitz, registered dietitian, CEO of Virtual Nutritionists, and author of The Core 3 Healthy Eating Plan, isn’t surprised to see people turning to Ozempic alternatives like this, but she doesn’t believe Ricezempic is a viable weight loss solution. 

“Ozempic hacks are on the rise, and Ricezempic is another example of how many people are searching for magic bullets for weight loss,” she said. “But weight loss is not so simple for the vast majority of people. It’s often due to stressful lifestyles, genetics, and other impeding factors.” 

Moskovitz described the trend as “low-hanging fruit, instilling a false sense of hope” in people who are living with obesity or overweight. 

Registered dietitian Kim Shapira echoed these thoughts. She said Ricezempic feels like a “reach.” 

“There is that great quote that you can’t outrun a bad diet, and I think if we can start talking about the sum total of a person’s diet and lifestyle choices in a positive, empowering way, we won’t see as many fads or have the need for Ozempic at all,” she noted. 

One of the reasons so many people are claiming that Ricezempic works as a weight loss aid is because of starch. The rice water is said to contain a naturally occurring resistant starch found in rice. 

“Resistant starch can slow down digestion, leading to better blood sugar levels and a longer sense of fullness,” Moskovitz explained. “This can make it easier to eat less and promote a calorie deficit, which is necessary for fat-burning.” 

Moskovitz said drugs like Ozempic and Wegovy work through similar mechanisms, although they are much stronger and also target areas in the brain that regulate appetite.

Similarly, Shapira pointed out that Ozempic is a medication that works on the emotional centers of the brain, turning down food noise, too. 

“This means when a person experiences discomfort, their mind is now able to differentiate hunger vs emotional needs for food,” she said. 

You won’t get the same effects by drinking rice water. 

Crucially, rice water isn’t food. “It’s a watery drink full of who knows how much actual resistant starch,” Shapira said. 

Potential benefits of drinking Ricezempic

So, Ricezempic is unlikely to promote significant weight loss, but it may have some other health benefits. 

“The main benefit of Ricezempic is consuming more resistant starch,” said Moskovitz. “Resistant starch not only promotes better blood sugar levels, but it can also benefit your gut health and bolster good gut bacteria proliferation.” 

This can increase the amount of good bacteria in your digestive tract, which is important for proper digestion, immunity, mental health, and metabolic health. 

Shapira said starches have so many benefits, but she says you’re better off getting them from food rather than rice water. 

“Eating rice as part of a balanced meal is beneficial,” she says. “So many people fear starches but we need these types of foods to be part of our diet to improve our immune function, heart, gut and brain health.” 

Shapira said starches that are resistant are essentially a dietary fiber. “Dietary fiber can improve our gut health in many ways, enhancing digestion and regulating bowels, insulin spikes, and blood sugar.” 

Potential health risks of Ricezempic  

That said, Ricezempic is not without potential health risks. In fact, Moskovitz said there are several risks involved with jumping on the Ricezempic bandwagon. 

“First, consuming anything uncooked or raw always leaves the possibility of food-borne illnesses, and rice is no exception,” she explained. “Second, rice is one of the leading sources of arsenic, and drinking rice-infused water can increase the concentration and exposure of this toxic heavy metal.” 

Moskovitz also said that replacing food with water means you’re reducing the amount of nutritious foods in your diet, which is never ideal.

Additionally, Shapira points out that drinking rice water can increase gas, bloating, and constipation if the rest of your diet isn’t balanced. 

The good news is that there are many ways to mimic the effects of Ricezempic in your diet without succumbing to this potentially dangerous trend.

“Eating a higher fiber and antioxidant-rich diet is the best way to boost gut health, promote more stable blood sugar levels, and make it easier to keep calories down and promote healthy, sustainable weight loss,” said Moskovitz.  

“You can also supplement with potato starch, which contains a significant amount of resistant starch, even more so than Ricezempic,” she added. 

Takeaway 

Ricezempic has been touted as an effective alternative to Ozempic, but it’s unlikely to mimic the effects of the drug.

It may slow digestion and improve gut health, but it’s unlikely to lead to significant weight loss, and it’s not the healthiest way to lose weight.