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Full House Star Dave Coulier Diagnosed with Stage 3 Non-Hodgkin’s Lymphoma

‘Full House’ stars Bob Saget (left), Dave Coulier (center), and John Stamos (right).
Full House cast members Bob Saget (left), Dave Coulier (center), and John Stamos (right). Kevork Djansezian/Getty Images
  • Actor Dave Coulier, known for playing Uncle Joey on Full House, announced he has stage 3 non-Hodgkin’s lymphoma.
  • Non-Hodkin’s lymphoma is a type of cancer that begins in the lymphatic system, part of the body’s immune system.
  • It can cause symptoms such as swollen lymph nodes in the neck, armpits, or groin, chest pain, or fever.
  • Treatment may include chemotherapy, radiation therapy, or targeted drug therapy.

Full House actor Dave Coulier, 65, has been diagnosed with stage 3 non-Hodgkin’s lymphoma.

The actor was diagnosed in October after a respiratory infection caused his lymph nodes to swell, reports PEOPLE

When the swelling increased rapidly, Coulier’s doctor advised him to undergo PET and CT scans and have a biopsy.

“Three days later, my doctors called me back and they said, ‘We wish we had better news for you, but you have non-Hodgkin’s lymphoma and it’s called B cell and it’s very aggressive,’” he told PEOPLE

What is non-Hodgkin’s lymphoma

Non-Hodgkin’s lymphoma (NHL) is a type of cancer that begins in the lymphatic system, which is part of the immune system that helps fight germs.

In this type of cancer, white blood cells (lymphocytes) grow abnormally and can lead to the growth of tumors in other parts of the body.

“The most common presentation of it is usually a swollen lymph node that is painless, and soft and rubbery,” said Jack Jacoub, MD, medical oncologist and medical director of MemorialCare Cancer Institute at Orange Coast and Saddleback Medical Centers in Orange County, Calif.

You have lymph nodes throughout the body, but the ones that you can easily feel with your hand are those in the neck, the armpits, and the groin, he said.

Other things can cause lymph nodes to become swollen, such as an infection. But in this case, they return to their normal size when the infection is over.

If a lymph node continues to be large or is painless, or if a lymph node is swollen on only one side of the body, then you should have it checked by a doctor, said Jacoub.

“Symptoms [of non-Hodgkin’s lymphoma] can also include things like fevers or sweats that you can’t explain or unexplained weight loss,” he told Healthline.

According to the American Cancer Society, non-Hodgkin’s lymphoma is one of the most common cancers in the United States, accounting for about 4% of all cancers.

There are many subtypes of non-Hodgkin’s lymphoma. Coulier has B cell lymphoma, which he described as “very aggressive,” reports PEOPLE. Most cases of non-Hodgkin’s lymphoma arise from B cells.

Coulier revealed that a test of his bone marrow showed that his cancer had not spread.

“At that point, my chances of curable went from something low to 90% range. And so that was a great day,” he told PEOPLE.

How non-Hodgkin’s lymphoma can be treated

Treatment for non-Hodgkin’s lymphoma depends upon the types of cells involved and how aggressive the lymphoma is.

If the lymphoma appears to be growing slowly and is not causing any signs or symptoms, you might not need immediate treatment. Instead, your doctor will monitor your condition every few months to see if your cancer is progressing.

But there are “more aggressive forms of lymphoma, where if you don’t do something, someone could die in a few months,” said Jacoub.

For more aggressive lymphomas, or if it is causing signs and symptoms, your doctor may recommend treatment such as:

  • chemotherapy
  • radiation therapy
  • targeted drug therapy
  • engineering your own immune cells to fight the lymphoma, known as chimeric antigen receptor (CAR)-T cell therapy
  • bone marrow transplant
  • immunotherapy

Coulier told PEOPLE that he started chemotherapy two weeks after his diagnosis, adding that he shaved his head as a “preemptive strike.”

In general, “treatment [for non-Hodgkin’s lymphoma] is extremely effective and can cure the majority of people,” said Jacoub, “even when it’s stage four.”

How to reduce your cancer risk

Most people diagnosed with non-Hodgkin’s lymphoma don’t have obvious factors that increase their risk of developing this type of cancer.

There are some factors that may increase the risk of non-Hodgkin’s lymphoma, although not everyone who has these risk factors will develop this cancer. These include:

  • Medications that suppress the immune system, such as those taken after an organ transplant.
  • Infections with certain bacteria and viruses, such as HIV, the Epstein-Barr virus, or the ulcer-causing Helicobacter pylori.
  • Certain chemicals, such as insect- and weed-killers.
  • Being older than 60 years.

“Sometimes certain families seem to have a higher risk of lymphoma. This is why knowing your family history is important,” said Jacoub. “But there is no hereditary disorder that has been identified to say that these people have a higher risk of lymphoma.”

You can’t eliminate your risk entirely. But you can help catch this and other cancers earlier — when they are easier to treat — by having concerning symptoms checked by a doctor and ensuring you have recommended screenings.

“Take great care of yourself because there’s a lot to live for,” Coulier told PEOPLE. “And if that means talking with your doctors or getting a mammogram or a breast exam or colonoscopy, it can really make a big change in your life.”

Jacoub also recommends living a healthy lifestyle in general, which can reduce the risk of other cancers.

“Limit drinking, stop smoking, lose weight as much as you can, exercise, and eat a plant-based or health-conscious diet,” he said.

Takeaway

Full House star Dave Coulier, 65, revealed that he has been diagnosed with stage 3 non-Hodgkin’s lymphoma. This type of cancer begins in the lymphatic system, which is part of the body’s immune system.

There are several types of non-Hodgkin’s lymphoma. Coulier has a type that arises from B cells. He revealed that his cancer is “very aggressive,” but a test showed that it had not spread to his bone marrow, which improves his chances of being treated successfully.

Coulier is undergoing chemotherapy for his cancer. Other treatments for non-Hodgkin’s lymphoma include radiation therapy, targeted drug therapy, and bone marrow transplant. 

Certain factors may increase the risk of developing this type of cancer, such as exposure to insect- and weed-killers. However, many people diagnosed with non-Hodgkin’s lymphoma have no known risk factors.

Full House Star Dave Coulier Diagnosed with Stage 3 Non-Hodgkin’s Lymphoma Read More »

Protein Diet Coke: Why the ‘Dirty Soda’ Is Taking Over TikTok

A can of Diet Coke and a bottle of Fairlife Core Power Protein Milk Shake.
Protein Diet Coke is a new twist on the ‘dirty soda’ trend that’s going viral on TikTok, but is the beverage really a healthy way to increase your protein intake that can aid with weight loss?
  • Protein Diet Coke has been gaining popularity on social media platforms like TikTok.
  • The drink is typically made by mixing a diet soft drink with a flavored protein shake.
  • Health experts say the trendy beverage can help people who are searching for ways to increase their daily protein intake, but adding Diet Coke to a protein shake does not add nutritional value.
  • Instead, experts recommend focusing on a balanced diet that includes natural high protein foods, especially for those who are increasing their daily protein to aid with weight loss.

Protein Diet Coke is the latest viral drink trend that’s taken over TikTok.

The beverage isn’t an official product of the Coca-Cola Company, but rather — as its name suggests — a combination of vanilla protein shake and Diet Coke.

Rebecca Gordan, an elementary school teacher from Utah, helped popularize the drink after a video she posted of herself enjoying a cup of the bubbly brew quickly went viral on TikTok.

Since then, videos of people trying the beverage and sharing their twists on the recipe have racked up millions of views on social media platforms, with many singing the drink’s praises as a delicious way of meeting their daily protein goals.

But is this trendy beverage really a “healthy” way of getting more protein in your diet?

Healthline spoke with nutritionists to help break down the pros and cons of Protein Diet Coke and reveal whether the viral soda is really worth a sip or one you should skip.

What is Protein Diet Coke?

Protein Diet Coke is an offshoot of the “dirty soda” trend, which exploded in popularity in 2022.

A “dirty soda” typically consists of a base soft drink with added flavored syrups, creams, or fruit juices — such as “Pilk” (Pepsi + milk) — similar to a root beer float or an alcohol-free mocktail.

Protein Diet Coke most often includes two simple ingredients: your choice of diet soft drink mixed with a bottle of ready-made protein shake.

Is Protein Diet Coke healthy?

“I wouldn’t label Protein Diet Coke as a healthy drink, but I don’t think that it’s unhealthy either,” said Destini Moody, a certified registered dietitian with Top Nutrition Coaching.

“I do find it a bit odd that we are mixing ready-to-drink protein in soda when we could just…drink the protein. The soda really doesn’t add anything of value considering it doesn’t have any calories and certainly doesn’t contain any additional protein or micronutrients.”

However, Moody noted that adding more protein to your diet in the form of whey protein shakes can pack a nutritious punch, especially if you’re trying to increase your daily protein intake.

She personally favors the Fairlife Core Power protein shakes, which are frequently used as a primary ingredient in many #proteindeitcoke videos posted on TikTok.

“They provide a good amount of high quality protein with all of the essential amino acids, half of your daily requirement of calcium, and can certainly go a long way in helping you stay full between meals,” said Moody.

Can Protein Diet Coke help you lose weight?

The Dietary Guidelines for Americans 2020–2025 suggest that adult males should eat at least 56 grams of protein daily, while adult females should eat at least 46 grams daily.

Research suggests, however, that eating higher amounts of protein may help you lose weight weight while retaining and building muscle mass.

Protein can help increase the body’s production of hormones such as GLP-1 and PYY, which can help you feel fuller longer.

Protein can also help reduce ghrelin (the “hunger hormone”).

Moody said that, when combined with a healthy diet and regular exercise, Protein Diet Coke may help aid with weight loss when consumed in moderation.

“Adding more protein to the diet in the form of whey protein shakes is always an excellent way to both build muscle and lose weight, so if mixing it with [diet] coke encourages more protein intake, I totally co-sign,” Moody said.

“Drinking this beverage between meals to curb cravings can help you lose weight compared to eating high calorie, carb-based snacks like chips and granola bars that leave you feeling hungry again shortly after you eat them.”

However, she stressed that it’s better to simply “drink the protein shake” without adding the additional soda.

“The Diet Coke does not add any additional benefit for either building muscle or weight loss. I’d label it as more of a flavor enhancer if anything,” she said.

Healthier ways of increasing your daily protein intake

While drinking beverages like Protein Diet Coke in moderation may help you beef up your daily protein intake, Michelle Routhenstein, a preventive cardiology dietitian and heart health expert at Entirely Nourished, said focusing on an overall healthy diet should be a higher priority.

“For sustainable muscle growth, weight loss, and overall health, it’s better to focus on a balanced meal post-exercise that ensures nutrient adequacy. This approach is more effective because it provides consistent, long-term results and fuels the body appropriately for optimal recovery,” she said.

She also noted that relying on protein shakes as meal replacements “could lead to nutritional gaps, hinder proper recovery post-workout, and potentially contribute to increased oxidative stress, which can impair muscle repair and overall recovery.”

Instead, she recommended increasing your protein intake by including more whole foods in your diet, such as:

  • lean meats
  • fish
  • eggs
  • dairy
  • legumes
  • nuts
  • seeds

Rather than drinking a Protein Diet Coke for a protein-rich snack, Routhenstein recommends trying healthier options like Greek yogurt, hard-boiled eggs, or edamame to meet your daily protein needs.

However, if you plan to incorporate protein shakes into your diet, Moody suggests beefing them up with healthier natural ingredients.

“I love to take strawberry core power shakes and blend it with frozen strawberries, bananas, Greek yogurt (for even more protein) and chia seeds,” Moody said.

“In this example, you are getting fiber, antioxidants, omega-3 fatty acids, and more micronutrients like calcium and Vitamin C along with the protein. You get none of that with Diet Coke.”

Takeaway

Protein Diet Coke has been gaining popularity on social media platforms like TikTok.

The drink is made by mixing a diet soft drink with a flavored protein shake.

Health experts say the trendy beverage can help people who are searching for ways to increase their daily protein intake, but adding Diet Coke to a protein shake does not add nutritional value.

Instead, focusing on a balanced diet that includes natural high protein foods is recommended, especially for those who are increasing their daily protein to aid with weight loss.

Protein Diet Coke: Why the ‘Dirty Soda’ Is Taking Over TikTok Read More »

How Health Insurance Can Save You Money on Medical Bills in Ghana

Secure Your Health, Save Your Money: A Guide to Choosing the Right Health Insurance in Ghana Health insurance in Ghana offers valuable financial protection, allowing residents to access essential healthcare services without the burden of overwhelming costs. As healthcare expenses continue to rise globally, having a robust health insurance plan is increasingly vital to avoid

How Health Insurance Can Save You Money on Medical Bills in Ghana Read More »

Americans Began Drinking More During the Pandemic, and They Haven’t Stopped

Female drinking wine with headphones and laptop on couch at home
Pandemic-era drinking habits persisted after the pandemic ended, particularly among adults in their 40s. Alistair Berg/Getty Images
  • A large new study shows that heavy drinking habits among adults in the U.S. have persisted beyond the COVID-19 pandemic.
  • Researchers say drinking levels stabilized before the pandemic, spiked during initial lockdowns, and persisted through at least 2022, if not longer.
  • Alcohol use is linked to over 200 diseases, injuries, and other health conditions, such as heart disease and different types of cancer.
  • Heavy alcohol use among adults under 50 rose by as much as 20%, with experts raising concerns over what they call a major public health issue.

Alcohol use has reached unprecedented levels despite there being no safe level of consumption.

Heavy drinking in the United States spiked during the COVID-19 pandemic and continued after it ended, according to Keck Medicine researchers at the University of Southern California (USC).

The large nationally representative study, published November 12 in the Annals of Internal Medicine, found that alcohol use among adults ages 18 and older rose by 4% from 2018 to 2020, with heavy alcohol use increasing by a staggering 20%. Researchers say the increases were sustained in 2022. 

“These numbers reflect an alarming public health issue that could result in severe health consequences for far too many people,” said Brian P. Lee, MD, MAS, a hepatologist and liver transplant specialist with Keck Medicine of USC and principal investigator of the study, said in a statement. “Our results suggest men and women under 50 are at special risk.” 

Alcohol use rising among young adults 

The population-based study included adults ages 18 and older who participated in the National Health Interview Survey from 2018 to 2022. 

The data included 24,965 respondents from 2018, 30,829 from 2020, and 26,806 from 2022.

The researchers divided respondents into two categories: having any alcohol use or heavy alcohol use within one year of the survey.

They defined heavy drinking as greater than or equal to five drinks a day or 15 drinks a week for males and greater than or equal to four drinks a day or eight drinks a week for females.  

The rise in alcohol use was seen across all age groups, genders, races, ethnicities, and regions of the U.S., except for Asian Americans and Native Americans. Adults ages 40-49 had the largest increase in heavy alcohol consumption.

The researchers did not assess what may have driven the increase but theorized the 2020 surge was linked to pandemic-related stressors that normalized heavy drinking, particularly among adults in their 40s.

“Heavy alcohol use increasing highest among young adults under 50 is something we see in the clinic and in the hospital and is showing up in the numbers,” Lee told Healthline.

“Three years ago, we showed there were increases in alcohol use,” Lee said of his prior research. “Now we’re showing that these increases are sustained. We’ve also shown that health consequences from increased alcohol use, whether it’s for liver transplants or alcohol-related mortality, have increased as well. It’s become quite clear that this has become a crisis.”

According to Lee, Americans have reached “historic highs” with their levels of alcohol consumption. “To me, that’s very concerning. We know that alcohol is a toxin. We know it has severe health consequences,” he said.

Alcohol is addictive

Alcohol use rose during the pandemic, likely due to stressors from lockdown to boredom to changes to the workplace or how children attended school, Lee noted.

“Before the pandemic, we were seeing stabilization toward a decline in heavy drinking. But the pandemic reversed that trend in very alarming ways,” he said.

For many people, alcohol is a maladaptive coping mechanism that may lead to alcohol use disorder (AUD), an addiction disorder

“We know that alcohol can become a habit, and even if the trigger that initially started a new habit is gone, the habit might still be there,” Lee said, offering a possible explanation as to why alcohol use has persisted.

“And we know that alcohol is addictive — it can start as a habit, and then it can become an addiction. The more ingrained and entrenched alcohol use becomes, the harder it is to stop,” he added.

Joseph R. Volpicelli MD, PhD, executive director at the Institute of Addiction Medicine, told Healthline that pandemic-era drinking persisted among adults, particularly those in their 40s, for several reasons. 

Increased stress, anxiety, and depression linked to work, parenting, reduced social interactions, and economic uncertainty may have led many people to use alcohol as a way to cope, he said.

“Habits formed during lockdowns and social isolation gave more opportunities to drink at home,” Volpicelli explained.

“Habits formed over months can become ingrained, making it hard to cut back when life returns to normal. Negative health effects from increased alcohol consumption might not show up immediately, allowing habits to continue unchecked until more serious problems arise,” he said.

Other health risks of alcohol use

Alcohol consumption is linked to over 200 diseases, injuries, and other health conditions, including heart disease and cancer, and is a leading preventable cause of illness and death in the U.S., according to the Centers for Disease Control and Prevention (CDC)

Alcohol use may also lead to or exacerbate mental health issues like depression and anxiety

Lee, who is a hepatologist, pointed out that nearly half of all liver-related deaths are tied to alcohol, with alcohol-related cirrhosis a leading cause of liver transplants.

“I think liver disease needs to be prioritized in terms of not only research but also screening and treatment for people with alcohol use,” he said.

Moderate drinkers also face potential health risks, with emerging evidence linking adverse health outcomes to moderate drinking

For instance, a recent study published in JAMA Network Open linked moderate alcohol consumption to a higher risk of cancer- and disease-related mortality. 

“The big picture of the health risks of alcohol should not be ignored,” David Cutler, MD, board certified family medicine physician at Providence Saint John’s Health Center in Santa Monica, CA, told Healthline in response to the JAMA study. 

“The evidence shows that alcohol, in any amount, can be harmful. We don’t tolerate it at all in pregnant women or minors. And prudent people should give serious thought to whether any alcohol consumption is in the best interest of their overall health,” Culter said.

Addressing heavy alcohol consumption as a public health issue may require targeted campaigns to raise awareness about the risks, Volpicelli noted, and improved access to mental health services.

“Encouraging healthy coping mechanisms and providing support for changing habits can help individuals reduce their drinking to pre-pandemic levels,” Volpicelli said.

Tips to reduce alcohol consumption

It’s never too late to stop drinking alcohol or cut back your consumption. Doing so could have immediate positive effects on your body, from repaired liver damage to a reduced risk of heart disease or improved brain health.

Volpicelli offered the following tips to cut back on drinking: 

  • Set clear goals and be mindful of drinking behavior.
  • Avoid triggers (i.e., people, places, or activities) for heavy drinking.
  • Develop healthy coping strategies for stress management (i.e., yoga, meditation, exercise).
  • Limit alcohol at home and stock up on non-alcoholic alternatives like sparkling water or teas.
  • Choose lower-alcohol options or dilute drinks.
  • Designate alcohol-free days.
  • Find support, such as talking with friends or family or joining support groups.
  • Seek professional help from a doctor or mental health professional.
  • Consider medications like naltrexone, which can help reduce cravings.
  • Develop alternatives to drinking, such as hobbies or social activities that don’t involve alcohol. 
  • Reward your progress and celebrate milestones when you reach your goals.

“Cutting back on alcohol is a personal journey, and different strategies can help you achieve your goals. Medications like naltrexone may offer additional support but should be part of a comprehensive plan that includes professional guidance and lifestyle changes,” Volpicelli said.

Takeaway

New research shows that heavy alcohol use among adults in the U.S. has persisted beyond the pandemic. Heavy alcohol use rose by 20% from 2018 to 2020 and remained stable in 2022, particularly among adults in their 40s. 

Alcohol use is associated with over 200 diseases, injuries, and other health conditions. The authors of the new study hope the findings will draw more awareness to the dangers of heavy drinking.

“We encourage healthcare providers to offer more screenings for harmful drinking as well as interventions for at-risk populations,” Lee said in a statement.

Americans Began Drinking More During the Pandemic, and They Haven’t Stopped Read More »

Vitamin D Supplements Lower Blood Pressure in Older Adults with Obesity, Study Finds

Vitamin D supplements.
New research finds that taking a daily vitamin D supplement may help lower blood pressure, especially for older adults with obesity. Tatjana Zlatkovic/Stocksy United
  • A new study found that taking vitamin D supplements was associated with lower blood pressure.
  • People with obesity and high blood pressure got the best results.
  • Better calcium regulation may be one of the main reasons for this effect.
  • Before supplementing with vitamin D, people should get their levels tested.

According to new research published on November 12, 2024, in the Journal of the Endocrine Society, supplementation with vitamin D plus calcium may help lower blood pressure in older adults with obesity (body mass index (BMI) greater than 30).

These supplements appeared to decrease both systolic blood pressure (the top number in a blood pressure reading) and diastolic blood pressure (the bottom number).

However, they noted that more is not necessarily better when it comes to lowering blood pressure. The effect was independent of the dose administered.

The people who took part in the study had high blood pressure.

The American Heart Association states that normal blood pressure is less than 120/80.

Anything greater than a systolic blood pressure of 130 or a diastolic blood pressure of 80 is deemed to be high blood pressure.

Vitamin D supplements linked with reduced blood pressure

The study included 221 individuals ages 65 and older who were taking vitamin D supplements.

They were all classified as having overweight (BMI greater than 25).

Additionally, they had a serum 25-hydroxy vitamin D level between 10 and 30 ng/mL. Anything below 30 ng/mL is considered insufficient, while values less than 20 are classified as vitamin D deficiency.

Two doses were examined: 600 IU/day (the Institutes of Medicine’s (IOM) recommended daily dose) and 3,750 IU/day. Both groups also took 250 mg of calcium citrate.

The study participants were followed for one year.

Upon comparing the two groups, they found that the higher dose of vitamin D did not provide greater benefit than the lower one.

However, both groups experienced a statistically significant drop in blood pressure, with their systolic blood pressure dropping by 3.5 mm Hg and their diastolic blood pressure dropping by 2.8 mm Hg.

The research further found that people with obesity and low vitamin D status improved their blood pressure the most.

Why vitamin D might affect blood pressure

Reimas Geiga, MD, a medical doctor, registered dietitian, and clinical nutritionist with Glowbar LDN, explained that vitamin D can affect blood pressure in several ways.

“One of the primary ways is by aiding in calcium regulation,” he said, “which is crucial for the contraction and relaxation of blood vessels. By improving vascular function, vitamin D could help reduce blood pressure.”

Additionally, in those with obesity, there is chronic, low-grade inflammation, said Geiga. This can impair blood vessel health, contributing to high blood pressure.

“Vitamin D has known anti-inflammatory properties that may help counteract this effect,” he explained. “Moreover, people with obesity are more likely to experience vitamin D deficiency because fat cells can store vitamin D, reducing its availability to the body.”

According to Geiga, supplementation back to adequate levels can help improve vascular health and lower blood pressure.

“Additionally, vitamin D influences the renin-angiotensin-aldosterone system, a key regulator of blood pressure,” he said. “Adequate vitamin D levels may reduce the activity of this system, leading to better blood pressure control.”

Are vitamin D supplements right for you?

Given that vitamin D is easy to obtain, patients may wonder how they can apply the study’s findings to their own lives.

Dr. Rita Hawle, a clinical dietitian and nutritionist with ClinicSpots, says the first step is determining whether you are actually low in vitamin D.

“A simple blood test can reveal any deficiency that may be contributing to blood pressure issues,” she said. “If levels are low, supplements or a bit of natural sunlight exposure (when safe) can help improve vitamin D status over time.”

However, she added that vitamin D supplementation really needs to be a part of a larger strategy.

“Blood pressure responds well to a combined approach—regular exercise, a heart-healthy diet, and effective weight management are all important for long-term benefits,” said Hawle.

Additionally, while the study looked at supplementation with 600 IU and 3,750 IU doses, she advises speaking with your physician about what is an appropriate dose for you. 

Vitamin D can accumulate in the human body, leading to a toxic build-up of calcium.

“This study provides encouraging insights,” Hawle concluded, “but it’s best to view vitamin D as part of a larger wellness plan, particularly for individuals managing both obesity and high blood pressure.”

Takeaway

A new study reports that older people with high blood pressure who were taking a vitamin D supplement along with calcium had lower blood pressure after a year.

The best results were experienced by people with obesity and lower initial levels of vitamin D at the start of the study.

Improved calcium regulation, lower inflammation, and reduced activity of the renin-angiotensin-aldosterone system could account for the reduction in blood pressure.

Experts recommend getting a blood test to determine if you are actually low in vitamin D and following your doctor’s advice regarding the dose you take before supplementing with it.

Supplementation should be part of a combined approach that includes a healthy diet, exercise, and weight management.

Vitamin D Supplements Lower Blood Pressure in Older Adults with Obesity, Study Finds Read More »

Ozempic and Wegovy May Provide Strong Relief from Osteoarthritis Knee Pain

A male wrapping a bandage around his knee.
Weight loss drugs like Ozempic and Wegovy have been liked with strong relief from osteoarthritis knee pain. Nazar Rybak/Getty Images
  • A new study suggests semaglutide use may help reduce severe knee pain.
  • People also lost weight during the course of the study.
  • The reduction in pain likely occurred because weight loss leads to less joint stress.
  • Semaglutide is also capable of balancing blood sugar and reducing inflammation.
  • Experts say we are likely to see continued advances with drugs like semaglutide.

While semaglutide (sold under the brand names Ozempic and Wegovy) is best known as a drug for the treatment of type 2 diabetes and obesity, research is increasingly finding that it may have applications outside of these uses.

For example, recent studies have found it could help reduce the risk of opioid overdose, early death, hidradenitis suppurativa, and Alzheimer’s disease.

Now, new research published on October 30, 2024, in The New England Journal of Medicine adds to the list, finding that once-weekly semaglutide usage was associated with relief from the severe knee pain associated with obesity and osteoarthritis.

According to the Arthritis Foundation, osteoarthritis is a “wear and tear” condition. It can cause:

  • cartilage breakdown
  • misshapen bones
  • chronic pain
  • inflammation
  • stiffness
  • loss of mobility

Obesity is one cause of osteoarthritis due to the strain that added weight put on joints, especially the knees, hips, and the spine.

How semaglutide use is linked to knee pain relief

The study enrolled 407 patients with an average age of 56 to evaluate the effects of semaglutide use on knee pain.

Their average body mass index (BMI) was 40.3. BMI of 30 or greater is classified as obesity.

Additionally, these individuals had an average WOMAC pain score of 70.9 on a scale of 0 to 100, with higher scores meaning worse pain.

All were diagnosed with moderate to severe knee pain.

The majority of study participants (81.6%) were female.

Everyone, regardless of whether they received semaglutide or not, was provided with counseling on diet and exercise.

Over the course of the 68-week study, people using semaglutide lost an average of 13.7% of their body weight compared with only 3.2% weight loss in those who did not use the drug.

Those using semaglutide also experienced an average reduction in their WOMAC pain score of 41.7 points, whereas the untreated group had an average decrease of 27.5 points.

Why semaglutide might provide relief for severe knee pain

Sandeep Singh, MS, MBBS, an orthopedic surgeon with Clinic Spots, said the biggest reason that Ozempic might provide pain relief really comes down to weight reduction.

“In osteoarthritis, every pound of weight lost takes about four pounds of pressure off the knee joints,” he explained. “So, the study’s average 13.7% weight loss likely brings considerable relief to the joints just from reducing that mechanical load.”

However, according to Singh, there may be more at play. The medication could have certain direct effects on relieving pain.

“We’re starting to see that GLP-1 receptor agonists, like Ozempic, may have anti-inflammatory effects,” he said, “which could help with knee pain beyond weight loss alone.”

Singh said that inflammation is a major factor in osteoarthritis which can lead to joint pain and deterioration.

“Even a slight reduction in inflammation can lead to a noticeable improvement in pain and stiffness,” he said.

Singh also pointed to semaglutide’s ability to stabilize blood sugar, which can bring down inflammation.

“This mix of lowered inflammation, reduced joint pressure, and better blood sugar control could potentially work together to relieve osteoarthritis symptoms,” he said.

How weight loss drugs may help improve future overall health

William Seeds, MD, a board certified orthopedic surgeon and the owner of Redox Medical Group, was enthusiastic about the findings of the study.

“This continues to be exciting evidence in the areas outside of weight loss that benefit improved quality of life issues and have profound effects on reducing healthcare dollars in the future second to the devastating effects of Osteoarthritis on the healthcare system,” he said.

Seeds added that he believes we are going to see continued advances in drugs like semaglutide.

“My belief is as we get better at improving the overall efficiencies of cellular mitochondrial function with continued advances in GLP1RAs we will be humbled by the continued beneficial signaling pathways that improve overall health,” he said.

Seeds further noted that we are seeing advancement in GLP-1 receptor agonists going from semaglutide (binds with GLP-1 receptors) to tirzepatide (binds with GLP-1 and GIP receptors) to retatrutide (binds with GLP-1, GIP, and glucagon receptors).

“The evolution from GLP-1 receptor agonists (semaglutide) to dual (tirzepatide) and triple agonist (retatrutide) represents a significant progression in enhanced cellular efficiencies, optimizing metabolic responses and therapeutic outcomes,” he said.

“These are exciting times in peptide development and clinical translation to life changing results!”

Takeaway

A study published in The New England Journal of Medicine found that using the type 2 diabetes and weight loss drug semaglutide was linked with improved pain scores in those with osteoarthritis, a painful and degenerative condition affecting the joints.

The weight loss engendered by this medication reduces the strain on joints.

Additionally, semaglutide helps to balance blood sugar and reduce inflammation. The sum of these effects is likely what reduces osteoarthritis pain in the knee.

Experts say we are likely to see continued beneficial effects from drugs like semaglutide due to the ways GLP-1 drugs impact signaling pathways.

Ozempic and Wegovy May Provide Strong Relief from Osteoarthritis Knee Pain Read More »

How Ozempic, GLP-1 Weight Loss Drugs Affect the Brain to Curb Substance Misuse

Female holding bag of groceries and cellphone walking down the street
A recent study found significant reductions in opioid overdose and alcohol misuse among people taking GLP-1 drugs like Ozempic. FreshSplash/Getty Images
  • A new study shows a 50% lower risk of alcohol intoxication among people with alcohol use disorder who take GLP-1 drugs prescribed for weight loss and diabetes.
  • The findings also show that people with opioid use disorder taking GLP-1 drugs like Ozempic had a 40% lower chance of an opioid overdose.
  • The study authors explained the medications interact with a part of the brain that can help suppress appetite, which may also help curb addictive behaviors.
  • Experts say the study results are promising, but more research is needed.

GLP-1 drugs prescribed for obesity and diabetes such as Ozempic and Mounjaro could help treat alcohol and drug use disorders, according to a new study.

The research, published in the journal Addiction, reports that people with substance abuse issues who take weight loss drugs with the active ingredients semaglutide and trizepatide had significantly lower rates of opioid overdoses and alcohol intoxication.

The reductions were seen only in more extreme instances involving opioid and alcohol misuse. While the results are nonetheless promising, further studies are needed to determine whether GLP-1 drugs can curb the desire for pain medications and alcohol.

“These medications are promising new pharmacological treatments for addictions, including (but not limited to) alcohol use disorder and opioid use disorder,” said Lorenzo Leggio, MD, a clinical researcher at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA). Leggio wasn’t involved in the study.

“That said, an important word of caution is the fact that we need double-blind placebo-controlled randomized trials to further test whether these medications work for patients with substance use disorders,” Leggio told Healthline.

Effects of weight loss drugs on substance use disorders

For their study, the researchers looked at 1.3 million health records compiled by Oracle’s Real-World Data system. The medical data for these cases was gathered between January 2014 and August 2022.

The researchers studied more than 500,000 people with a history of opioid use disorder. Of them, about 8,100 had a prescription for a GLP-1 drug, such as Ozempic, Mounjaro, and Wegovy.

The study authors report that people with opioid use disorder who take a GLP-1 drug had a 40% lower rate of opioid overdose compared to those who did not have a prescription.

The researchers also examined more than 800,000 people with a history of alcohol use disorder. Of them, about 5,600 had a prescription for a GLP-1 medication.

The study authors stated that people with alcohol use disorder who take a weight-loss drug had a 50% lower rate of alcohol intoxication when compared with those with didn’t have a prescription.

The researchers noted that this is the first large-scale study with humans on the potential use of weight loss drugs to reduce addiction risks.

“This study suggests that patients with heroin or alcohol addiction who are prescribed Ozempic (typically for diabetes or obesity) are less likely to be hospitalized for heroin overdose or alcohol intoxication, respectively,” Matt Field, a professor of psychology at the University of Sheffield in the United Kingdom, told Healthline. Field wasn’t involved in the study.

“The findings add to those from other studies, particularly animal research, which suggest that this and similar drugs might one day be prescribed to help people with addiction,” Field added.

How GLP-1 drugs alter the brain’s reward response

The researchers explained that GLP-1 medications interact with the mesolimbic system in the brain to reduce appetite and trigger satisfaction after eating.

They said the mesolimbic system overlaps with the brain processes that govern addictive behaviors.

According to a news release, the overlap suggests that GLP-1 RAs and similar drugs may change the reward-response pathways that are linked to substance misuse.

Leggio said that although more study is needed, the future looks promising for the use of these medications to curb addiction.

“The preclinical and human data we have so far suggest that these medications may be beneficial for addiction in general by curbing cravings and reducing alcohol drinking, opioid use, smoking, etc.,” Leggio said.

Field noted a word of caution about the findings. “The outcomes are very extreme instances of substance intoxication,” he said. 

“Those outcomes are very different from the outcomes used when researchers test new treatments for addiction, in which case we might look at whether the treatment helps people to stop taking the substance altogether (complete abstinence), or if it helps people to reduce the amount of substance they consume, or how often they consume it,” Field continued.

“Those things could not be measured in this study. This leaves open the possibility that while Ozempic may (for reasons currently unknown) prevent people from taking so much alcohol or heroin that they overdose and end up in hospital, it may not help them to reduce their substance use, or to abstain altogether,” Field noted.

What to know about alcohol use disorder

It’s estimated that nearly 29 million people ages 12 and older in the United States have alcohol use disorder. Around 17 million are male and 12 million are female.

“Alcohol use disorder is a medical condition characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences,” according to the NIAAA.

The condition, considered a brain disorder, can be mild, moderate, or severe. Factors that can contribute to developing alcohol use disorder include:

  • drinking at an early age
  • genetics and family history
  • mental health conditions
  • history of trauma

Medical professionals generally ask people a series of questions to determine if they have developed alcohol use disorder. Among the questions:

  • Have you had times when you ended up drinking more or longer than you intended?
  • Have you ever wanted a drink so badly you couldn’t think of anything else?
  • Have you ever continued to drink even though it was causing problems with family and friends?
  • Have you found yourself in a situation while drinking that increased your chances of getting injured?

There are treatments available to treat alcohol use disorder. Three medications are currently approved by the Food and Drug Administration (FDA) to help treat alcohol misuse:

Mental health resources like behavioral therapy and mutual support groups can also be helpful.

What to know about opioid use disorder

It’s estimated that about 4% of adults in the U.S. need some form of treatment for opioid use disorder. That is more than 9 million people.

In 2022, more than 80,000 opioid-involved overdose deaths were reported in the United States, the highest number on record.

Opioid use disorder, which is considered a brain disorder, is characterized by Yale Medicine as “continuing opioid use despite harmful consequences.”

The symptoms of being addicted to these pain medications include:

  • physical dependence
  • loss of control in taking opioids
  • inability to complete tasks at home, work, or school
  • skipping important events or meetings

Some medications are used to help treat opioid use disorder, including:

Leggio noted the current medications can be effective in treating addiction, but they need to be more widely available.

“These medications are not widely used as they should and indeed, it’s very important to increase efforts toward expanding the use of these approved effective treatments for our patients,” he said.

A growing number of health benefits for GLP-1 drugs

Recent research reported that GLP-1 drugs with the active ingredient trizepatide such as Mounjaro and Zepbound were effective in helping people maintain weight loss over three years.

Medications with the active ingredient semaglutide, such as Ozempic and Wegovy, are also proven to be effective in helping people lose weight over an extended period.

Experts have said this consistent weight loss may also help lower the risk of developing type 2 diabetes.

2023 study also indicated that weight loss drugs with semaglutide may help reduce the risk of some cancers.

Now, pharmaceutical companies are looking into the possibility that their GLP-1 medications may also help treat alcohol and opioid use disorders.

In addition to the new research, another recent study reported that Ozempic and Wegovy may help lower the risk of opioid overdose.

Takeaway

In a new study, researchers say people with alcohol use disorder who take GLP-1 drugs had a 50% lower risk of alcohol intoxication compared to people not taking the medications.

The researchers also reported that people with opioid use disorder taking GLP-1 drugs such as Ozempic had a 40% lower chance of an opioid overdose compared to people who aren’t taking the medications.

The study authors said GLP-1 drugs are effective in a part of the brain that can help suppress appetite. They said the medications may also work in other nearby parts of the brain to help curb addictive behaviors.

Experts say the study results are promising, but more research is needed.

How Ozempic, GLP-1 Weight Loss Drugs Affect the Brain to Curb Substance Misuse Read More »

James Van Der Beek’s Colon Cancer Diagnosis Highlights Alarming Trend In Young People

Actor James Van Der Beek
The former “Dawson’s Creek” star’s diagnosis is part of a startling trend in rising colon cancer cases among young adults. Casey Flanigan/IndieWire/Penske Media via Getty Images
  • Actor James Van Der Beek, formerly of “Dawson’s Creek, announced that he is battling colorectal cancer.
  • The 47-year-old actor’s diagnosis is part of a startling trend in rising colon cancer cases among young adults.
  • In 2021, the recommended screening age was lowered from 50 to 45 in response to the growing number of early-onset colon cancer cases.
  • Colorectal cancer is one of the leading causes of cancer-related deaths, but is also highly treatable if found early.

Television and film star James Van Der Beek announced that he is battling colorectal cancer. 

The 47-year-old former “Dawson’s Creek” actor announced the diagnosis on his personal Instagram page and later confirmed it to People. Van Der Beek had been keeping the news private but was compelled to come forward to prevent a tabloid from running the story.

“I’ve been dealing with this privately until now, getting treatment and dialing in my overall health with greater focus than ever before. I’m in a good place and feeling strong,” Van Der Beek wrote in the post. “It’s been quite the initiation, and I’ll tell you more when I’m ready,” he wrote.

Van Der Beek added that he hopes to be able to tell his story on his own terms and raise awareness about the disease.

“I hope because of his story that others will reevaluate some of their symptoms they may be having, and hopefully, meet with a physician to investigate further to ensure maybe that they can be diagnosed earlier rather than later,” Cathy Eng, MD, FACP, executive director of the Young Adult Cancers Program at Vanderbilt-Ingram Cancer Center, told Healthline.

Colon cancer increasing in young adults

Colon cancer (CRC) has become more prevalent among younger adults in recent years.

Between 1995 and 2019, the number of CRC diagnoses in individuals under 55 has doubled. The number of deaths associated with CRC in those younger than 50 has also increased by 1% annually since 2005.

In response, the U.S. Preventive Services Task Force issued a new recommendation to lower the age to start screening for colorectal cancer from 50 to 45 years of age. 

“CRC has now become the leading cause of cancer deaths in men and women under the age of 50 years old. That is a remarkable finding, and this certainly goes with that trend,” Christina Annunziata, MD, PhD, senior vice president of Extramural Discovery Science at the American Cancer Society, told Healthline, referring to Van Der Beek’s diagnosis.

According to the American Cancer Society, risk factors associated with the increasing incidence of colon cancer among younger adults include excess body weight, processed meat consumption, and smoking.

Colon cancer is also more common in males than females. Racial and ethnic factors are also prominent indicators of risk: Alaska Natives, American Indians, and Blacks have the highest incidences of CRC.

“We do not know exactly why this is happening, but I would definitely say it is multifactorial at the end of the day. The numbers are concerning and alarming when you’re seeing a young patient in your clinic with stage 4 disease that is surgically unresectable and incurable,” Eng said.

Screening for colorectal cancer

Colorectal cancer affects the cells of the colon (large intestine) and rectum.

CRC is the fourth most common type of cancer in the United States but is the second-leading cause of all cancer-related deaths. Despite being one of the most deadly cancers, it is highly treatable when it is diagnosed early.

Current guidelines recommend people with an average colon cancer risk begin regular screening at age 45.

At 47, Van Der Beek was narrowly within that window. The actor didn’t offer any additional details about the diagnosis, nor did he specify what treatment options he’s pursuing. 

Colorectal cancer most often starts out as small growths known as polyps, which vary in size and shape from bumps and flat growths to mushroom-shaped growths.

Most polyps may be benign, but some will eventually develop into cancer. The size of a polyp and the number of polyps in the colon may be indicators of the likelihood of the polyp developing into cancer. 

Without knowing the stage of Van Der Beek’s cancer, it’s impossible to say when it developed.

According to Eng, it takes an average of 5 to 10 years for a noncancerous polyp to develop into cancer, meaning that polyps could have been present as early as a person’s late 30s. “You can have a polyp without having any symptoms,” Eng noted.

Signs and symptoms of colon cancer

There are numerous signs and symptoms of colorectal cancer. However, many of them are nonspecific, meaning they could be the result of other conditions and, therefore, difficult to diagnose.

“Some of the early warning signs may include blood in the stool, abdominal pain and cramping, weight loss, and fatigue,” Christopher Chen, MD, an assistant professor of Oncology and director of Early Drug Development at the Stanford Cancer Institute, Stanford Medicine, told Healthline.

Rectal bleeding is the most obvious symptom of colorectal cancer and should be pursued with a doctor.

Ovunc Bardakcioglu, MD, FACS, chief of colorectal surgery at the Kirk Kerkorian School of Medicine at the University of Las Vegas, told Healthline that people should not only be aware of these symptoms but pay particular attention to their frequency and duration.

Occasional abdominal pain isn’t out of the ordinary, but persistent cramping could warrant a discussion with a healthcare professional.

“I’ve seen in my practice patients having these symptoms for a long period of time, up to a year, and I think it would be very important, even in that young population — 20s and 30s — to get an immediate full workup,” Bardakcioglu said.

Takeaway

Former “Dawson’s Creek” actor James Van Der Beek was forced to go public with his colorectal cancer diagnosis in response to a tabloid planning to run the story.

Van Der Beek’s diagnosis is part of a growing trend in rising colorectal cancer cases among young people. Since 1995, the number of diagnoses of early-onset colon cancer in people under 55 has doubled.

Colorectal cancer affects the cells of the colon (large intestine) and rectum. It is the second leading cause of all cancer-related deaths.

Signs and symptoms of colorectal include rectal bleeding, unexplained weight loss, and persistent abdominal pain. If you’re experiencing any of these symptoms, you should reach out to a healthcare professional as soon as possible.

James Van Der Beek’s Colon Cancer Diagnosis Highlights Alarming Trend In Young People Read More »

Abortion Rights Expanded in 7 States, But Change Will Take Time

protesters holding abortion rights-related flags
Seven out of 10 states that had abortion on the ballot during the 2024 presidential election voted to expand abortion access. 
Kent Nishimura/Getty Images
  • Abortion was a key focal point of the 2024 presidential election, with abortion rights ballot measures passing in 7 of 10 states.
  • Donald Trump’s victory over Kamala Harris marks a turning point for American politics and an uncertain future for reproductive rights.
  • While Trump has said he won’t sign a nationwide abortion ban, experts remain skeptical of the impending administration.

President-elect Donald Trump’s sweeping win over Vice President Kamala Harris ushered in a new era of uncertainty in the battle for reproductive rights.

Abortion became a major focal point of the November 2024 election following the 2022 reversal of Roe v. Wade, with abortion rights ballot measures prevailing in 7 of 10 states.

Despite these victories for abortion protection, they won’t change overnight. States that passed abortion rights amendments in 2022 and 2023, like Ohio, Michigan, and Missouri, were mired in legal red tape. Months would pass before any new abortion protection policies could take effect, KFF Health News reports

“Every day we live under Trump’s abortion bans, more people will suffer and die,” Alexis McGill Johnson, president and CEO of the Planned Parenthood Action Fund (PPAF) said in a statement

“Abortion is powerful and popular. The American people do not want politicians making their health care decisions. In poll after poll, voters said abortion mattered to them — mattered in their lives and mattered in the voting booth… the majority of voters were clear and unequivocal: people are dying. People are suffering. Fix this,” McGill Johnson continued.

Abortion protective ballot measures pass in 7 states

Abortion was on the ballot for voters in 10 states during the 2024 presidential election. 

According to the Guttmacher Institute, the following states passed abortion rights ballot measures:

In Florida, an amendment to limit government interference with abortion fell short of the needed 60% support at just over 57%. 

In Nebraska, where both abortion protective and anti-abortion measures were on the ballot. The anti-abortion measure passed. 

In South Dakota, an amendment to prohibit the state from restricting abortion during the first trimester failed to pass. The state currently has an abortion ban that only allows abortions to save the life of a pregnant person.

Changes to abortion access will take time

In the seven states that saw victories for abortion access, the bans or restrictions in place are not automatically repealed, which means change will likely take some time. Abortion advocates will have to petition courts to overturn the anti-abortion laws in place to align with the new amendments, according to the Associated Press.

Access to abortion clearly continues to mobilize voters across the country, even those where a measure did not pass this year,” Candace Gibson, director of State Policy at the Guttmacher Institute, said in a statement shared with Healthline.

“As we prepare for an incoming Trump Administration and additional attacks on reproductive freedom, we must continue to push policymakers at all levels to protect reproductive freedom, support state-based organizations, and donate to abortion funds,” Gibson continued.

Sarah Prager, MD, a professor in the Department of Obstetrics and Gynecology at the University of Washington School of Medicine, told Healthline she was “extremely gratified” by the passed ballot measures.

“This clearly shows that the American people want access to abortion in spite of what some legislators and legislatures are saying,” Prager said. 

“I do think that over time, more state efforts to increase access to abortion and/or codify the right to abortion in state constitutions will be successful. However, that is not an option in all states — 24 states do not allow for citizen-initiated statewide initiatives or ballot measures,” Prager continued, noting how newly implemented barriers like the 60% majority rule in Florida caused the ballot measure to fail with just 57% of the vote. 

“We will continue to see positive and successful efforts to restore the right to abortion and reproductive health care, but in the meantime, patients are suffering and even dying,” she said.

Will Trump ban abortion nationwide?

The impending 2025 Republican administration could further impact abortion access, even in states without bans, experts say.

If Congress were to approve a national abortion ban, it could potentially override any state protections, NBC reports

Access to abortion medication, such as mifepristone, could also face scrutiny during Trump’s second term as president.

The uncertainty that lay ahead is rooted in the president-elect’s shifting position on whether he’d sign a national abortion ban. 

During the tail-end of his campaign, Trump reversed his stance and said he wouldn’t and that the issue should continue to be left up to the states. Whether he’ll remain true to this position is unclear.

“Donald Trump ran from his record and said he would not ban abortion nationwide. Planned Parenthood Action Fund is going to hold him to that every day for the next four years,” McGill Johnson said.

Prager said she is certain Trump will sign a nationwide abortion ban.

“It may be called something else, it may not completely ban all abortions, but it will be introduced early, and if Republicans control the House and Senate, it will pass and Trump will sign it. It may take some time for that to go through the courts, but with our current Supreme Court, I have no doubt it will go through,” Prager noted.

“Of course, those are my beliefs — I cannot predict the future, but I can be informed by the past.”

Takeaway

Abortion rights ballot measures passed in 7 of 10 states during the November 2024 election. President-elect Donald Trump’s victory over Vice President Kamala Harris signals an uncertain future for reproductive rights.

While Trump claims he won’t sign a nationwide abortion ban, experts remain wary. If Congress were to approve such a ban, it could potentially override any state-level abortion protections in place.

Abortion Rights Expanded in 7 States, But Change Will Take Time Read More »

Quincy Jones Lived with Brain Aneurysms, Diabetes for Years Before His Death at 91

Quincy Jones
Music legend Quincy Jones, known for producing Michael Jackson’s “Thriller” album and other hits, managed living with two brain aneurysms and type 2 diabetes years before his death at 91. Emma McIntyre/Getty Images for Celebrity Fight Night
  • Quincy Jones, the iconic music mogul who produced Michael Jackson’s “Thriller,” died recently at the age of 91.
  • Jones lived with type 2 diabetes for years and previously shared how he approached challenges managing the condition.
  • He also spoke publicly about health scares, including two brain aneurysms in 1974 and a diabetic coma in 2015.

Legendary music producer Quincy Jones, who worked with Michael Jackson, Frank Sinatra, and many others, died this week at age 91. Jones, who had type 2 diabetes, was public throughout his life about his health problems.

He died on Sunday, November 3, at home with his family. With a decades-spanning career, Jones was a titan of the music industry, receiving 28 Grammy Awards and countless other accolades.

He worked with artists like Ray Charles, Frank Sinatra, and Michael Jackson, for whom he produced “Thriller” in 1982, which became the best-selling album of all time.

But, alongside his many successes, Jones experienced health setbacks as well, including brain aneurysms and receiving a type 2 diabetes diagnosis. 

Two aneurysms nearly killed Jones in 1974

In 1974, Jones had two brain aneurysms at the age of 41.

Brain aneurysms are deformities, resembling balloons or berries, in the arterial wall of the brain that fill with blood. If an aneurysm bursts, the resulting brain damage can be fatal without immediate medical attention. 

Jones recalled the incident in a post on his Facebook page in 2018.

“It felt like a shotgun was fired inside of my head. While operating for 7.5 hours, my doctors discovered a second aneurysm that was ready to blow, so they had to schedule a second operation. During this time, it didn’t look too promising, so my friends planned a memorial service for me at The Shrine in LA, & I basically attended my own funeral,” he wrote.

Though he recalls having a mere one in a hundred chance of surviving, the operations were both successful. But, to prevent further recurrences, doctors advised him that he could no longer play the trumpet, which he’d played since his teenage years. 

His doctors had used metal clips to close off the aneurysms in his brain and were worried that intracranial pressure caused by playing the instrument would dislodge them.

In an interview with GQ magazine, Jones said he swore to give up his trumpet playing. But, while on tour in Japan shortly after recovering, he decided to pick it up again. This time, though, he felt an immediate pain in his head from the pressure.

After that scare, he put down the trumpet for good.

How Quincy Jones learned to manage type 2 diabetes

Jones lived with and managed type 2 diabetes for years, which required him to make major lifestyle changes. 

In 2015, he went into a diabetic coma, a moment he recalled in a Facebook post from 2019 as “what should’ve been my last breath.”

“A diabetic coma refers to when you have diabetes and that you lose consciousness for some reason. It can be due to low blood sugar, or it can be due to very high blood sugar,” Sun Kim, MD, an endocrinologist and associate professor of medicine at Stanford Medicine, told Healthline.

“It’s very serious. If you don’t present to medical attention, there’s a high degree of mortality associated with it,” she added.

Following the incident, Jones decided to give up drinking alcohol for good.

“I had enough alcohol to last multiple lifetimes, & the doctors told me I had to call it quits!! After substituting drinking with eating sugar-free popsicles, I lost 50 pounds, & started feeling 37 again,” he wrote.

Kevin Peterson, MD, MPH, Vice President of primary care at the American Diabetes Association, told Healthline that quitting drinking is an important step in managing diabetes, alongside other lifestyle changes.

“The most important lifestyle changes are maintaining a healthy diet and a healthy weight.  Maintaining blood sugars in a healthy range is more difficult with alcohol consumption since alcohol changes the way that the liver processes blood sugar. Unhealthy drinking habits make it difficult to maintain healthy blood sugars and pose a health risk in themselves,” he said.

Complications commonly associated with type 2 diabetes

Type 2 diabetes is a complex disease that can significantly increase an individual’s risk for other health problems. These risks include:

  • Heart and blood vessel damage
  • Kidney damage
  • Eye damage
  • Foot damage
  • Dementia

Individuals with diabetes are two to four times more likely to develop cardiovascular disease, including heart attack and stroke. The disease is also a leading cause of blindness in adults due to a condition known as diabetic retinopathy, which is when the blood vessels in the retina of the eye are damaged.

“Diabetes affects the entire body. In particular, it damages blood vessels. Over time, this damage can take a toll on eyes, kidneys, and on the nerves. People with diabetes are at a higher risk for heart attacks, strokes, and other forms of cardiovascular disease,” said Peterson.

However, there are ways to manage the condition, including lifestyle changes, exercise, and medication.

“The way you’re supposed to live with diabetes is how we’re all supposed to live, but it just becomes more real when you have diabetes. We all could eat less sugar. We could all eat less processed foods. We could all eat less refined carbs and more whole grains,” said Kim.

Doctors and researchers also continue to make improvements to diabetes care and management year after year.

“Many advances in diabetes have occurred since Mr. Quincy was first diagnosed with diabetes several decades ago.  New labs, medicines, and devices make the treatment of diabetes simpler and more effective now than it has ever been,” said Peterson.

The bottom line

Quincy Jones, the famed producer behind Michael Jackson’s “Thriller,” has died this month at the age of 91.

Jones lived with type 2 diabetes for many years and learned to manage it through lifestyle changes, including avoiding drinking alcohol.

He was also public with other health scares throughout his life, including having two brain aneurysms in 1974 and falling into a diabetic coma in 2015.

Type 2 diabetes is a complex disease that damages the blood vessels and increases the risk of multiple other conditions, including cardiovascular disease and diabetic retinopathy.

Quincy Jones Lived with Brain Aneurysms, Diabetes for Years Before His Death at 91 Read More »